Preclinical In Vitro and In Vivo Evidence of an Antitumor Effect of CX-4945, a Casein Kinase II Inhibitor, in Cholangiocarcinoma()()()

PURPOSE: We investigated the antitumor effect of the casein kinase II (CK2) inhibitor CX-4945 on cholangiocarcinoma (CCA). METHODS: We assessed the effect of CX-4945 alone and/or in combination with gemcitabine and cisplatin on cell viability, colony formation, and apoptosis of CCA cell lines and on...

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Bibliografiska uppgifter
I publikationen:Transl Oncol
Huvudupphovsmän: Zakharia, Kais, Miyabe, Katsuyuki, Wang, Yu, Wu, Dehai, Moser, Catherine D., Borad, Mitesh J., Roberts, Lewis R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Neoplasia Press 2018
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Original article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187100/
https://ncbi.nlm.nih.gov/pubmed/30316146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2018.09.005
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