Preclinical In Vitro and In Vivo Evidence of an Antitumor Effect of CX-4945, a Casein Kinase II Inhibitor, in Cholangiocarcinoma()()()

PURPOSE: We investigated the antitumor effect of the casein kinase II (CK2) inhibitor CX-4945 on cholangiocarcinoma (CCA). METHODS: We assessed the effect of CX-4945 alone and/or in combination with gemcitabine and cisplatin on cell viability, colony formation, and apoptosis of CCA cell lines and on...

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Bibliographic Details
Published in:Transl Oncol
Main Authors: Zakharia, Kais, Miyabe, Katsuyuki, Wang, Yu, Wu, Dehai, Moser, Catherine D., Borad, Mitesh J., Roberts, Lewis R.
Format: Artigo
Language:Inglês
Published: Neoplasia Press 2018
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Original article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6187100/
https://ncbi.nlm.nih.gov/pubmed/30316146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2018.09.005
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