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The casein kinase 2 inhibitor, CX-4945, as an anti-cancer drug in treatment of human hematological malignancies

The casein kinase 2 (CK2) protein kinase is a pro-survival kinase and therapeutic target in treatment of various human cancers. CK2 overexpression has been demonstrated in hematological malignancies, including chronic lymphocytic leukemia, chronic myeloid leukemia, acute lymphoblastic leukemia, acut...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Chon, Hae J., Bae, Kyoung J., Lee, Yura, Kim, Jiyeon
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4379896/
https://ncbi.nlm.nih.gov/pubmed/25873900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00070
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