Novel insights about the MDM2/MDM4 heterodimer

by Moretti, Fabiola
Published in Mol Cell Oncol (2015)

Role of Sex in the Therapeutic Targeting of p53 Circuitry

by Mancini, Francesca, Giorgini, Ludovica, Teveroni, Emanuela, Pontecorvi, Alfredo, Moretti, Fabiola
Published in Front Oncol (2021)

MDM2–MDM4 molecular interaction investigated by atomic force spectroscopy and surface plasmon resonance

by Moscetti, Ilaria, Teveroni, Emanuela, Moretti, Fabiola, Bizzarri, Anna Rita, Cannistraro, Salvatore
Published in Int J Nanomedicine (2016)

The beneficial effect of Zinc(II) on low-dose chemotherapeutic sensitivity involves p53 activation in wild-type p53-carrying colorectal cancer cells

by Garufi, Alessia, Ubertini, Valentina, Mancini, Francesca, D’Orazi, Valerio, Baldari, Silvia, Moretti, Fabiola, Bossi, Gianluca, D’Orazi, Gabriella
Published in J Exp Clin Cancer Res (2015)

Signaling through estrogen receptors modulates telomerase activity in human prostate cancer

by Nanni, Simona, Narducci, Michela, Della Pietra, Linda, Moretti, Fabiola, Grasselli, Annalisa, De Carli, Piero, Sacchi, Ada, Pontecorvi, Alfredo, Farsetti, Antonella
Published 2002

Effect of p53 activation through targeting MDM2/MDM4 heterodimer on T regulatory and effector cells in the peripheral blood of Type 1 diabetes patients

by Pellegrino, Marsha, Traversi, Gianandrea, Arena, Andrea, Cappa, Marco, Rosado, M. Manuela, Andreani, Marco, Delfino, Domenico V., Moretti, Fabiola, Fierabracci, Alessandra
Published in PLoS One (2020)

Inhibition of the mTOR pathway and reprogramming of protein synthesis by MDM4 reduce ovarian cancer metastatic properties

by Lucà, Rossella, Assenza, Maria Rita, Maiullari, Fabio, Pieroni, Luisa, Maiullari, Silvia, Federici, Giulia, Marini, Federica, Rizzi, Roberto, Urbani, Andrea, Soddu, Silvia, Moretti, Fabiola
Published in Cell Death Dis (2021)

Intake of Boron, Cadmium, and Molybdenum enhances rat thyroid cell transformation

by Luca, Emilia, Fici, Laura, Ronchi, Anna, Marandino, Ferdinando, Rossi, Esther Diana, Caristo, Maria Emiliana, Malandrino, Pasqualino, Russo, Marco, Pontecorvi, Alfredo, Vigneri, Riccardo, Moretti, Fabiola
Published in J Exp Clin Cancer Res (2017)

MDM4 actively restrains cytoplasmic mTORC1 by sensing nutrient availability

by Mancini, Francesca, Teveroni, Emanuela, Di Conza, Giusy, Monteleone, Valentina, Arisi, Ivan, Pellegrino, Marsha, Buttarelli, Marianna, Pieroni, Luisa, D’Onofrio, Mara, Urbani, Andrea, Pontecorvi, Alfredo, Mazzone, Massimiliano, Moretti, Fabiola
Published in Mol Cancer (2017)

Sempervirine inhibits RNA polymerase I transcription independently from p53 in tumor cells

by Caggiano, Cinzia, Guida, Eugenia, Todaro, Federica, Bielli, Pamela, Mori, Mattia, Ghirga, Francesca, Quaglio, Deborah, Botta, Bruno, Moretti, Fabiola, Grimaldi, Paola, Rossi, Pellegrino, Jannini, Emmanuele A., Barchi, Marco, Dolci, Susanna
Published in Cell Death Discov (2020)

Analysis of human MDM4 variants in papillary thyroid carcinomas reveals new potential markers of cancer properties

by Prodosmo, Andrea, Giglio, Simona, Moretti, Sonia, Mancini, Francesca, Barbi, Flavia, Avenia, Nicola, Di Conza, Giusy, Schünemann, Holger J., Pistola, Lorenza, Ludovini, Vienna, Sacchi, Ada, Pontecorvi, Alfredo, Puxeddu, Efisio, Moretti, Fabiola
Published 2008

Association of TrkA and APP Is Promoted by NGF and Reduced by Cell Death-Promoting Agents

by Canu, Nadia, Pagano, Ilaria, La Rosa, Luca Rosario, Pellegrino, Marsha, Ciotti, Maria Teresa, Mercanti, Delio, Moretti, Fabiola, Sposato, Valentina, Triaca, Viviana, Petrella, Carla, Maruyama, Ichiro N., Levi, Andrea, Calissano, Pietro
Published in Front Mol Neurosci (2017)

Maternal thyroid hormones are transcriptionally active during embryo–foetal development: results from a novel transgenic mouse model

by Nucera, Carmelo, Muzzi, Patrizia, Tiveron, Cecilia, Farsetti, Antonella, Regina, Federico La, Foglio, Benedetta, Shih, Shou-Ching, Moretti, Fabiola, Pietra, Linda Della, Mancini, Francesca, Sacchi, Ada, Trimarchi, Francesco, Vercelli, Alessandro, Pontecorvi, Alfredo
Published 2010

MDM4 (MDMX) localizes at the mitochondria and facilitates the p53-mediated intrinsic-apoptotic pathway

by Mancini, Francesca, Di Conza, Giusy, Pellegrino, Marsha, Rinaldo, Cinzia, Prodosmo, Andrea, Giglio, Simona, D'Agnano, Igea, Florenzano, Fulvio, Felicioni, Lara, Buttitta, Fiamma, Marchetti, Antonio, Sacchi, Ada, Pontecorvi, Alfredo, Soddu, Silvia, Moretti, Fabiola
Published 2009

The mTOR and PP2A Pathways Regulate PHD2 Phosphorylation to Fine-Tune HIF1α Levels and Colorectal Cancer Cell Survival under Hypoxia

by Di Conza, Giusy, Trusso Cafarello, Sarah, Loroch, Stefan, Mennerich, Daniela, Deschoemaeker, Sofie, Di Matteo, Mario, Ehling, Manuel, Gevaert, Kris, Prenen, Hans, Zahedi, Rene Peiman, Sickmann, Albert, Kietzmann, Thomas, Moretti, Fabiola, Mazzone, Massimiliano
Published in Cell Rep (2017)

Estrogens enhance myoblast differentiation in facioscapulohumeral muscular dystrophy by antagonizing DUX4 activity

by Teveroni, Emanuela, Pellegrino, Marsha, Sacconi, Sabrina, Calandra, Patrizia, Cascino, Isabella, Farioli-Vecchioli, Stefano, Puma, Angela, Garibaldi, Matteo, Morosetti, Roberta, Tasca, Giorgio, Ricci, Enzo, Trevisan, Carlo Pietro, Galluzzi, Giuliana, Pontecorvi, Alfredo, Crescenzi, Marco, Deidda, Giancarlo, Moretti, Fabiola
Published in J Clin Invest (2017)

Estrogens Counteract Platinum-Chemosensitivity by Modifying the Subcellular Localization of MDM4

by Lucà, Rossella, di Blasio, Giorgia, Gallo, Daniela, Monteleone, Valentina, Manni, Isabella, Fici, Laura, Buttarelli, Marianna, Ciolli, Germana, Pellegrino, Marsha, Teveroni, Emanuela, Maiullari, Silvia, Ciucci, Alessandra, Apollo, Alessandro, Mancini, Francesca, Gentileschi, Maria Pia, Zannoni, Gian Franco, Pontecorvi, Alfredo, Scambia, Giovanni, Moretti, Fabiola
Published in Cancers (Basel) (2019)