Association of TrkA and APP Is Promoted by NGF and Reduced by Cell Death-Promoting Agents

The amyloid precursor protein (APP) interacts with the tropomyosin receptor kinase A (TrkA) in normal rat, mouse, and human brain tissue but not in Alzheimer’s disease (AD) brain tissue. However, it has not been reported whether the two proteins interact directly, and if so, which domains are involv...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Canu, Nadia, Pagano, Ilaria, La Rosa, Luca Rosario, Pellegrino, Marsha, Ciotti, Maria Teresa, Mercanti, Delio, Moretti, Fabiola, Sposato, Valentina, Triaca, Viviana, Petrella, Carla, Maruyama, Ichiro N., Levi, Andrea, Calissano, Pietro
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5281621/
https://ncbi.nlm.nih.gov/pubmed/28197073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00015
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