Association of TrkA and APP Is Promoted by NGF and Reduced by Cell Death-Promoting Agents

The amyloid precursor protein (APP) interacts with the tropomyosin receptor kinase A (TrkA) in normal rat, mouse, and human brain tissue but not in Alzheimer’s disease (AD) brain tissue. However, it has not been reported whether the two proteins interact directly, and if so, which domains are involv...

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Bibliografiske detaljer
Udgivet i:Front Mol Neurosci
Main Authors: Canu, Nadia, Pagano, Ilaria, La Rosa, Luca Rosario, Pellegrino, Marsha, Ciotti, Maria Teresa, Mercanti, Delio, Moretti, Fabiola, Sposato, Valentina, Triaca, Viviana, Petrella, Carla, Maruyama, Ichiro N., Levi, Andrea, Calissano, Pietro
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5281621/
https://ncbi.nlm.nih.gov/pubmed/28197073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00015
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