Estrogens enhance myoblast differentiation in facioscapulohumeral muscular dystrophy by antagonizing DUX4 activity

Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant neuromuscular disorder that is characterized by extreme variability in symptoms, with females being less severely affected than males and presenting a higher proportion of asymptomatic carriers. The sex-related factors involved i...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Teveroni, Emanuela, Pellegrino, Marsha, Sacconi, Sabrina, Calandra, Patrizia, Cascino, Isabella, Farioli-Vecchioli, Stefano, Puma, Angela, Garibaldi, Matteo, Morosetti, Roberta, Tasca, Giorgio, Ricci, Enzo, Trevisan, Carlo Pietro, Galluzzi, Giuliana, Pontecorvi, Alfredo, Crescenzi, Marco, Deidda, Giancarlo, Moretti, Fabiola
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373881/
https://ncbi.nlm.nih.gov/pubmed/28263188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI89401
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