Hypoxic regulation of the noncoding genome and NEAT1

Por Choudhry, Hani, Mole, David R.
Publicado no Brief Funct Genomics (2016)

Characterization of different isoforms of the HIF prolyl hydroxylase PHD1 generated by alternative initiation

Por Tian, Ya-Min, Mole, David R., Ratcliffe, Peter J., Gleadle, Jonathan M.
Publicado em 2006

High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq

Por Schödel, Johannes, Oikonomopoulos, Spyros, Ragoussis, Jiannis, Pugh, Christopher W., Ratcliffe, Peter J., Mole, David R.
Publicado em 2011

Regulation of Type II Transmembrane Serine Proteinase TMPRSS6 by Hypoxia-inducible Factors: NEW LINK BETWEEN HYPOXIA SIGNALING AND IRON HOMEOSTASIS

Por Lakhal, Samira, Schödel, Johannes, Townsend, Alain R. M., Pugh, Christopher W., Ratcliffe, Peter J., Mole, David R.
Publicado em 2011

Hypoxia, Hypoxia-inducible Transcription Factors, and Renal Cancer

Por Schödel, Johannes, Grampp, Steffen, Maher, Eamonn R., Moch, Holger, Ratcliffe, Peter J., Russo, Paul, Mole, David R.
Publicado no Eur Urol (2015)

Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts

Por Mole, David R., Blancher, Christine, Copley, Richard R., Pollard, Patrick J., Gleadle, Jonathan M., Ragoussis, Jiannis, Ratcliffe, Peter J.
Publicado em 2009

Unlocking the complexity of hypoxia non-coding transcriptome landscape of breast cancer

Por Choudhry, Hani, Schodel, Johannes, Albukhari, Ashwag, Oikonomopoulos, Spyros, Haider, Syed, Buffa, Francesca, Ragousis, Ioannis, Mole, David R, Harris, Adrian L
Publicado em 2014

Extensive regulation of the non-coding transcriptome by hypoxia: role of HIF in releasing paused RNApol2

Por Choudhry, Hani, Schödel, Johannes, Oikonomopoulos, Spyros, Camps, Carme, Grampp, Steffen, Harris, Adrian L, Ratcliffe, Peter J, Ragoussis, Jiannis, Mole, David R
Publicado em 2014

Capture‐C reveals preformed chromatin interactions between HIF‐binding sites and distant promoters

Por Platt, James L, Salama, Rafik, Smythies, James, Choudhry, Hani, Davies, James OJ, Hughes, Jim R, Ratcliffe, Peter J, Mole, David R
Publicado no EMBO Rep (2016)

Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression

Por Schödel, Johannes, Bardella, Chiara, Sciesielski, Lina K, Brown, Jill M, Pugh, Chris W, Buckle, Veronica, Tomlinson, Ian P, Ratcliffe, Peter J, Mole, David R
Publicado em 2012

Destruction of a distal hypoxia response element abolishes trans-activation of the PAG1 gene mediated by HIF-independent chromatin looping

Por Schörg, Alexandra, Santambrogio, Sara, Platt, James L., Schödel, Johannes, Lindenmeyer, Maja T., Cohen, Clemens D., Schrödter, Katrin, Mole, David R., Wenger, Roland H., Hoogewijs, David
Publicado no Nucleic Acids Res (2015)

The Lysyl Oxidases LOX and LOXL2 Are Necessary and Sufficient to Repress E-cadherin in Hypoxia: INSIGHTS INTO CELLULAR TRANSFORMATION PROCESSES MEDIATED BY HIF-1

Por Schietke, Ruth, Warnecke, Christina, Wacker, Ingrid, Schödel, Johannes, Mole, David R., Campean, Valentina, Amann, Kerstin, Goppelt-Struebe, Margarete, Behrens, Jürgen, Eckardt, Kai-Uwe, Wiesener, Michael S.
Publicado em 2010

Unlocking the complexity of hypoxia non-coding transcriptome landscape of breast cancer

Por Choudhry, Hani, Schodel, Johannes, Albukhari, Ashwag, Oikonomopoulos, Spyros, Haider, Syed, Moralli, Daniela, Camps, Carme, Buffa, Francesca, Ratcliffe, Peter, Ragousis, Ioannis, Mole, David R, Harris, Adrian L
Publicado em 2014

Tuning the Transcriptional Response to Hypoxia by Inhibiting Hypoxia-inducible Factor (HIF) Prolyl and Asparaginyl Hydroxylases

Por Chan, Mun Chiang, Ilott, Nicholas E., Schödel, Johannes, Sims, David, Tumber, Anthony, Lippl, Kerstin, Mole, David R., Pugh, Christopher W., Ratcliffe, Peter J., Ponting, Chris P., Schofield, Christopher J.
Publicado no J Biol Chem (2016)

Archean komatiite volcanism controlled by the evolution of early continents

Por Mole, David R., Fiorentini, Marco L., Thebaud, Nicolas, Cassidy, Kevin F., McCuaig, T. Campbell, Kirkland, Christopher L., Romano, Sandra S., Doublier, Michael P., Belousova, Elena A., Barnes, Stephen J., Miller, John
Publicado em 2014

Genetic variation at the 8q24.21 renal cancer susceptibility locus affects HIF binding to a MYC enhancer

Por Grampp, Steffen, Platt, James L., Lauer, Victoria, Salama, Rafik, Kranz, Franziska, Neumann, Viviana K., Wach, Sven, Stöhr, Christine, Hartmann, Arndt, Eckardt, Kai-Uwe, Ratcliffe, Peter J., Mole, David R., Schödel, Johannes
Publicado no Nat Commun (2016)

Integrated analysis of microRNA and mRNA expression and association with HIF binding reveals the complexity of microRNA expression regulation under hypoxia

Por Camps, Carme, Saini, Harpreet K, Mole, David R, Choudhry, Hani, Reczko, Martin, Guerra-Assunção, José Afonso, Tian, Ya-Min, Buffa, Francesca M, Harris, Adrian L, Hatzigeorgiou, Artemis G, Enright, Anton J, Ragoussis, Jiannis
Publicado em 2014

Clinical features of the pathogenic m.5540G>A mitochondrial transfer RNA tryptophan gene mutation

Por Ng, Yi Shiau, Hardy, Steven A., Shrier, Venice, Quaghebeur, Gerardine, Mole, David R., Daniels, Matthew J., Downes, Susan M., Freebody, Jane, Fratter, Carl, Hofer, Monika, Nemeth, Andrea H., Poulton, Joanna, Taylor, Robert W.
Publicado no Neuromuscul Disord (2016)