Integrated analysis of microRNA and mRNA expression and association with HIF binding reveals the complexity of microRNA expression regulation under hypoxia

BACKGROUND: In mammalians, HIF is a master regulator of hypoxia gene expression through direct binding to DNA, while its role in microRNA expression regulation, critical in the hypoxia response, is not elucidated genome wide. Our aim is to investigate in depth the regulation of microRNA expression b...

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Detalhes bibliográficos
Main Authors: Camps, Carme, Saini, Harpreet K, Mole, David R, Choudhry, Hani, Reczko, Martin, Guerra-Assunção, José Afonso, Tian, Ya-Min, Buffa, Francesca M, Harris, Adrian L, Hatzigeorgiou, Artemis G, Enright, Anton J, Ragoussis, Jiannis
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3928101/
https://ncbi.nlm.nih.gov/pubmed/24517586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-28
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