Extensive regulation of the non-coding transcriptome by hypoxia: role of HIF in releasing paused RNApol2

Hypoxia is central to both ischaemic and neoplastic diseases. However, the non-coding transcriptional response to hypoxia is largely uncharacterized. We undertook integrated genomic analyses of both non-coding and coding transcripts using massively parallel sequencing and interfaced this data with p...

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Autori principali: Choudhry, Hani, Schödel, Johannes, Oikonomopoulos, Spyros, Camps, Carme, Grampp, Steffen, Harris, Adrian L, Ratcliffe, Peter J, Ragoussis, Jiannis, Mole, David R
Natura: Artigo
Lingua:Inglês
Pubblicazione: BlackWell Publishing Ltd 2014
Soggetti:
Scientific Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983684/
https://ncbi.nlm.nih.gov/pubmed/24363272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embr.201337642
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