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Hypoxia, Hypoxia-inducible Transcription Factors, and Renal Cancer
CONTEXT: Renal cancer is a common urologic malignancy, and therapeutic options for metastatic disease are limited. Most clear cell renal cell carcinomas (ccRCC) are associated with loss of von Hippel-Lindau tumor suppressor (pVHL) function and deregulation of hypoxia pathways. OBJECTIVE: This review...
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Publicado no: | Eur Urol |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5012644/ https://ncbi.nlm.nih.gov/pubmed/26298207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2015.08.007 |
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