Identification of Highly Selective and Potent Histone Deacetylase 3 Inhibitors Using Click Chemistry-Based Combinatorial Fragment Assembly

Por Suzuki, Takayoshi, Kasuya, Yuki, Itoh, Yukihiro, Ota, Yosuke, Zhan, Peng, Asamitsu, Kaori, Nakagawa, Hidehiko, Okamoto, Takashi, Miyata, Naoki
Publicado em 2013

FFA1-selective agonistic activity based on docking simulation using FFA1 and GPR120 homology models

Por Takeuchi, Masato, Hirasawa, Akira, Hara, Takafumi, Kimura, Ikuo, Hirano, Tatsuya, Suzuki, Takayoshi, Miyata, Naoki, Awaji, Takeo, Ishiguro, Masaji, Tsujimoto, Gozoh
Publicado em 2013

Loss of Deacetylation Activity of Hdac6 Affects Emotional Behavior in Mice

Por Fukada, Masahide, Hanai, Atsuko, Nakayama, Atsuo, Suzuki, Takayoshi, Miyata, Naoki, Rodriguiz, Ramona M., Wetsel, William C., Yao, Tso-Pang, Kawaguchi, Yoshiharu
Publicado em 2012

Targeting the PELP1-KDM1 axis as a potential therapeutic strategy for breast cancer

Por Cortez, Valerie, Mann, Monica, Tekmal, Seshidhar, Suzuki, Takayoshi, Miyata, Naoki, Rodriguez-Aguayo, Cristian, Lopez-Berestein, Gabriel, Sood, Anil K, Vadlamudi, Ratna K
Publicado em 2012

Correction: Targeting the PELP1-KDM1 axis as a potential therapeutic strategy for breast cancer

Por Cortez, Valerie, Mann, Monica, Tekmal, Seshidhar, Suzuki, Takayoshi, Miyata, Naoki, Rodriguez-Aguayo, Cristian, Lopez-Berestein, Gabriel, Sood, Anil K, Vadlamudi, Ratna K
Publicado em 2012

NCL1, a highly selective lysine-specific demethylase 1 inhibitor, suppresses prostate cancer without adverse effect

Por Etani, Toshiki, Suzuki, Takayoshi, Naiki, Taku, Naiki-Ito, Aya, Ando, Ryosuke, Iida, Keitaro, Kawai, Noriyasu, Tozawa, Keiichi, Miyata, Naoki, Kohri, Kenjiro, Takahashi, Satoru
Publicado no Oncotarget (2014)

KDM1 is a novel therapeutic target for the treatment of gliomas

Por Sareddy, Gangadhara R., Nair, Binoj C., Krishnan, Samaya K., Gonugunta, Vijay K., Zhang, Quan-guang, Suzuki, Takayoshi, Miyata, Naoki, Brenner, Andrew J., Brann, Darrell W., Vadlamudi, Ratna K.
Publicado em 2012

Histone Deacetylase Inhibitor Valproic Acid Promotes the Differentiation of Human Induced Pluripotent Stem Cells into Hepatocyte-Like Cells

Por Kondo, Yuki, Iwao, Takahiro, Yoshihashi, Sachimi, Mimori, Kayo, Ogihara, Ruri, Nagata, Kiyoshi, Kurose, Kouichi, Saito, Masayoshi, Niwa, Takuro, Suzuki, Takayoshi, Miyata, Naoki, Ohmori, Shigeru, Nakamura, Katsunori, Matsunaga, Tamihide
Publicado em 2014

The KDM1A histone demethylase is a promising new target for the epigenetic therapy of medulloblastoma

Por Pajtler, Kristian W, Weingarten, Christina, Thor, Theresa, Künkele, Annette, Heukamp, Lukas C, Büttner, Reinhard, Suzuki, Takayoshi, Miyata, Naoki, Grotzer, Michael, Rieb, Anja, Sprüssel, Annika, Eggert, Angelika, Schramm, Alexander, Schulte, Johannes H
Publicado em 2013

Identification of the KDM2/7 Histone Lysine Demethylase Subfamily Inhibitor and its Antiproliferative Activity

Por Suzuki, Takayoshi, Ozasa, Hiroki, Itoh, Yukihiro, Zhan, Peng, Sawada, Hideyuki, Mino, Koshiki, Walport, Louise, Ohkubo, Rei, Kawamura, Akane, Yonezawa, Masato, Tsukada, Yuichi, Tumber, Anthony, Nakagawa, Hidehiko, Hasegawa, Makoto, Sasaki, Ryuzo, Mizukami, Tamio, Schofield, Christopher J., Miyata, Naoki
Publicado em 2013