The KDM1A histone demethylase is a promising new target for the epigenetic therapy of medulloblastoma

BACKGROUND: Medulloblastoma is a leading cause of childhood cancer-related deaths. Current aggressive treatments frequently lead to cognitive and neurological disabilities in survivors. Novel targeted therapies are required to improve outcome in high-risk medulloblastoma patients and quality of life...

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Bibliographische Detailangaben
Hauptverfasser: Pajtler, Kristian W, Weingarten, Christina, Thor, Theresa, Künkele, Annette, Heukamp, Lukas C, Büttner, Reinhard, Suzuki, Takayoshi, Miyata, Naoki, Grotzer, Michael, Rieb, Anja, Sprüssel, Annika, Eggert, Angelika, Schramm, Alexander, Schulte, Johannes H
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3893444/
https://ncbi.nlm.nih.gov/pubmed/24252778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-1-19
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