BET bromodomain protein inhibition is a therapeutic option for medulloblastoma

Medulloblastoma is the most common malignant brain tumor of childhood, and represents a significant clinical challenge in pediatric oncology, since overall survival currently remains under 70%. Patients with tumors overexpressing MYC or harboring a MYC oncogene amplification have an extremely poor p...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Henssen, Anton, Thor, Theresa, Odersky, Andrea, Heukamp, Lukas, El-Hindy, Nicolai, Beckers, Anneleen, Speleman, Frank, Althoff, Kristina, Schäfers, Simon, Schramm, Alexander, Sure, Ulrich, Fleischhack, Gudrun, Eggert, Angelika, Schulte, Johannes H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2013
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3875771/
https://ncbi.nlm.nih.gov/pubmed/24231268
Tagiau: Ychwanegu Tag
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