Histone Deacetylase Inhibitor Valproic Acid Promotes the Differentiation of Human Induced Pluripotent Stem Cells into Hepatocyte-Like Cells

In this study, we aimed to elucidate the effects and mechanism of action of valproic acid on hepatic differentiation from human induced pluripotent stem cell-derived hepatic progenitor cells. Human induced pluripotent stem cells were differentiated into endodermal cells in the presence of activin A...

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Detalhes bibliográficos
Main Authors: Kondo, Yuki, Iwao, Takahiro, Yoshihashi, Sachimi, Mimori, Kayo, Ogihara, Ruri, Nagata, Kiyoshi, Kurose, Kouichi, Saito, Masayoshi, Niwa, Takuro, Suzuki, Takayoshi, Miyata, Naoki, Ohmori, Shigeru, Nakamura, Katsunori, Matsunaga, Tamihide
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119015/
https://ncbi.nlm.nih.gov/pubmed/25084468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104010
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