An Efficient Method for Differentiation of Human Induced Pluripotent Stem Cells into Hepatocyte-like Cells Retaining Drug Metabolizing Activity

The use of human induced pluripotent stem (iPS) cells would be of great value for a variety of applications involving drug development studies. Several reports have been published on the differentiation of human iPS cells into hepatocyte-like cells; however, the cells were insufficient for applicati...

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Udgivet i:Drug Metab Pharmacokinet
Main Authors: Kondo, Yuki, Iwao, Takahiro, Nakamura, Katsunori, Sasaki, Takamitsu, Takahashi, Shogo, Kamada, Noboru, Matsubara, Tsutomu, Gonzalez, Frank J., Akutsu, Hidenori, Miyagawa, Yoshitaka, Okita, Hajime, Kiyokawa, Nobutaka, Toyoda, Masashi, Umezawa, Akihiro, Nagata, Kiyoshi, Matsunaga, Tamihide, Ohmori, Shigeru
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6594155/
https://ncbi.nlm.nih.gov/pubmed/24334537
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