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Stability of genomic imprinting in human induced pluripotent stem cells

BACKGROUND: hiPSCs are generated through epigenetic reprogramming of somatic tissue. Genomic imprinting is an epigenetic phenomenon through which monoallelic gene expression is regulated in a parent-of-origin-specific manner. Reprogramming relies on the successful erasure of marks of differentiation...

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Detalhes bibliográficos
Main Authors: Hiura, Hitoshi, Toyoda, Masashi, Okae, Hiroaki, Sakurai, Masahiro, Miyauchi, Naoko, Sato, Akiko, Kiyokawa, Nobutaka, Okita, Hajime, Miyagawa, Yoshitaka, Akutsu, Hidenori, Nishino, Koichiro, Umezawa, Akihiro, Arima, Takahiro
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3751563/
https://ncbi.nlm.nih.gov/pubmed/23631808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-14-32
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