Efficient Generation of Hepatoblasts From Human ES Cells and iPS Cells by Transient Overexpression of Homeobox Gene HEX

Human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) have the potential to differentiate into all cell lineages, including hepatocytes, in vitro. Induced hepatocytes have a wide range of potential application in biomedical research, drug discovery, and the treatment of liver...

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Autors principals: Inamura, Mitsuru, Kawabata, Kenji, Takayama, Kazuo, Tashiro, Katsuhisa, Sakurai, Fuminori, Katayama, Kazufumi, Toyoda, Masashi, Akutsu, Hidenori, Miyagawa, Yoshitaka, Okita, Hajime, Kiyokawa, Nobutaka, Umezawa, Akihiro, Hayakawa, Takao, Furue, Miho K, Mizuguchi, Hiroyuki
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2011
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034848/
https://ncbi.nlm.nih.gov/pubmed/21102561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.241
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