Efficient Generation of Functional Hepatocytes From Human Embryonic Stem Cells and Induced Pluripotent Stem Cells by HNF4α Transduction

Hepatocyte-like cells from human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) are expected to be a useful source of cells drug discovery. Although we recently reported that hepatic commitment is promoted by transduction of SOX17 and HEX into human ESC- and iPSC-derived cell...

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Hlavní autoři: Takayama, Kazuo, Inamura, Mitsuru, Kawabata, Kenji, Katayama, Kazufumi, Higuchi, Maiko, Tashiro, Katsuhisa, Nonaka, Aki, Sakurai, Fuminori, Hayakawa, Takao, Kusuda Furue, Miho, Mizuguchi, Hiroyuki
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2012
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255576/
https://ncbi.nlm.nih.gov/pubmed/22068426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.234
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