Targeting Protein Kinases with Selective and Semi-Promiscuous Covalent Inhibitors

מאת Miller, Rand M., Taunton, Jack
הוצא לאור ב Methods Enzymol (2014)

Leveraging Chemotype-specific Resistance for Drug Target Identification and Chemical Biology

מאת Kapoor, Tarun M., Miller, Rand M.
הוצא לאור ב Trends Pharmacol Sci (2017)

Electrophilic Fragment-Based Design of Reversible Covalent Kinase Inhibitors

מאת Miller, Rand M., Paavilainen, Ville O., Krishnan, Shyam, Serafimova, Iana M., Taunton, Jack
יצא לאור 2013

Design of Reversible, Cysteine-Targeted Michael Acceptors Guided by Kinetic and Computational Analysis

מאת Krishnan, Shyam, Miller, Rand M., Tian, Boxue, Mullins, R. Dyche, Jacobson, Matthew P., Taunton, Jack
יצא לאור 2014

Correction to “Design of Reversible, Cysteine-Targeted Michael Acceptors Guided by Kinetic and Computational Analysis”

מאת Krishnan, Shyam, Miller, Rand M., Tian, Boxue, Mullins, R. Dyche, Jacobson, Matthew P., Taunton, Jack
הוצא לאור ב J Am Chem Soc (2014)

Covalent Docking of Large Libraries for the Discovery of Chemical Probes

מאת London, Nir, Miller, Rand M., Krishnan, Shyam, Uchida, Kenji, Irwin, John J., Eidam, Oliv, Gibold, Lucie, Cimermančič, Peter, Bonnet, Richard, Shoichet, Brian K., Taunton, Jack
הוצא לאור ב Nat Chem Biol (2014)

Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles

מאת Serafimova, Iana M., Pufall, Miles A., Krishnan, Shyam, Duda, Katarzyna, Cohen, Michael S., Maglathlin, Rebecca L., McFarland, Jesse M., Miller, Rand M., Frödin, Morten, Taunton, Jack
יצא לאור 2012

Cytoplasmic Dynein Antagonists with Improved Potency and Isoform Selectivity

מאת See, Stephanie K., Hoogendoorn, Sascha, Chung, Andrew H., Ye, Fan, Steinman, Jonathan B., Sakata-Kato, Tomoyo, Miller, Rand M., Cupido, Tommaso, Zalyte, Ruta, Carter, Andrew P., Nachury, Maxence V., Kapoor, Tarun M., Chen, James K.
הוצא לאור ב ACS Chem Biol (2015)

Chromatin kinases act on transcription factors and histone tails in regulation of inducible transcription

מאת Josefowicz, Steven Z., Shimada, Miho, Armache, Anja, Li, Charles H., Miller, Rand M., Lin, Shu, Yang, Aerin, Dill, Brian D., Molina, Henrik, Park, Hee-Sung, Garcia, Benjamin A., Taunton, Jack, Roeder, Robert G., Allis, C. David
הוצא לאור ב Mol Cell (2016)

Chemical structure-guided design of dynapyrazoles, cell-permeable dynein inhibitors with a unique mode of action

מאת Steinman, Jonathan B, Santarossa, Cristina C, Miller, Rand M, Yu, Lola S, Serpinskaya, Anna S, Furukawa, Hideki, Morimoto, Sachie, Tanaka, Yuta, Nishitani, Mitsuyoshi, Asano, Moriteru, Zalyte, Ruta, Ondrus, Alison E, Johnson, Alex G, Ye, Fan, Nachury, Maxence V, Fukase, Yoshiyuki, Aso, Kazuyoshi, Foley, Michael A, Gelfand, Vladimir I, Chen, James K, Carter, Andrew P, Kapoor, Tarun M
הוצא לאור ב eLife (2017)