Anti‐tumor efficacy of a novel CLK inhibitor via targeting RNA splicing and MYC‐dependent vulnerability

Por Iwai, Kenichi, Yaguchi, Masahiro, Nishimura, Kazuho, Yamamoto, Yukiko, Tamura, Toshiya, Nakata, Daisuke, Dairiki, Ryo, Kawakita, Yoichi, Mizojiri, Ryo, Ito, Yoshiteru, Asano, Moriteru, Maezaki, Hironobu, Nakayama, Yusuke, Kaishima, Misato, Hayashi, Kozo, Teratani, Mika, Miyakawa, Shuichi, Iwatani, Misa, Miyamoto, Maki, Klein, Michael G, Lane, Wes, Snell, Gyorgy, Tjhen, Richard, He, Xingyue, Pulukuri, Sai, Nomura, Toshiyuki
Publicado no EMBO Mol Med (2018)

Chemical structure-guided design of dynapyrazoles, cell-permeable dynein inhibitors with a unique mode of action

Por Steinman, Jonathan B, Santarossa, Cristina C, Miller, Rand M, Yu, Lola S, Serpinskaya, Anna S, Furukawa, Hideki, Morimoto, Sachie, Tanaka, Yuta, Nishitani, Mitsuyoshi, Asano, Moriteru, Zalyte, Ruta, Ondrus, Alison E, Johnson, Alex G, Ye, Fan, Nachury, Maxence V, Fukase, Yoshiyuki, Aso, Kazuyoshi, Foley, Michael A, Gelfand, Vladimir I, Chen, James K, Carter, Andrew P, Kapoor, Tarun M
Publicado no eLife (2017)