Learning from the past for TB drug discovery in the future

Por Mikušová, Katarína, Ekins, Sean
Publicado no Drug Discov Today (2016)

Biosynthesis of Galactan in Mycobacterium tuberculosis as a Viable TB Drug Target?

Por Konyariková, Zuzana, Savková, Karin, Kozmon, Stanislav, Mikušová, Katarína
Publicado no Antibiotics (Basel) (2020)

Purification and characterization of the acyltransferase involved in biosynthesis of the major mycobacterial cell envelope glycolipid - monoacylated phosphatidylinositol dimannosid...

Por Svetlíková, Zuzana, Baráth, Peter, Jackson, Mary, Korduláková, Jana, Mikušová, Katarína
Publicado em 2014

Synthesis, docking study and biological evaluation of ᴅ-fructofuranosyl and ᴅ-tagatofuranosyl sulfones as potential inhibitors of the mycobacterial galactan synthesis targeting the...

Por Baráth, Marek, Jakubčinová, Jana, Konyariková, Zuzana, Kozmon, Stanislav, Mikušová, Katarína, Bella, Maroš
Publicado no Beilstein J Org Chem (2020)

Investigation of ABC transporter from mycobacterial arabinogalactan biosynthetic cluster

Por Dianišková, Petronela, Korduláková, Jana, Škovierová, Henrieta, Kaur, Devinder, Jackson, Mary, Brennan, Patrick J., Mikušová, Katarína
Publicado no Gen Physiol Biophys (2011)

Galactosyl Transferases in Mycobacterial Cell Wall Synthesis

Por Beláňová, Martina, Dianišková, Petronela, Brennan, Patrick J., Completo, Gladys C., Rose, Natisha L., Lowary, Todd L., Mikušová, Katarína
Publicado em 2008

Identification of a Novel Galactosyl Transferase Involved in Biosynthesis of the Mycobacterial Cell Wall

Por Mikušová, Katarína, Beláňová, Martina, Korduláková, Jana, Honda, Kristine, McNeil, Michael R., Mahapatra, Sebabrata, Crick, Dean C., Brennan, Patrick J.
Publicado em 2006

GtrA Protein Rv3789 Is Required for Arabinosylation of Arabinogalactan in Mycobacterium tuberculosis

Por Kolly, Gaëlle S., Mukherjee, Raju, Kilacsková, Emöke, Abriata, Luciano A., Raccaud, Mahé, Blaško, Jaroslav, Sala, Claudia, Dal Peraro, Matteo, Mikušová, Katarína, Cole, Stewart T.
Publicado no J Bacteriol (2015)

N-Acetylglucosamine-1-Phosphate Transferase, WecA, as a Validated Drug Target in Mycobacterium tuberculosis

Por Huszár, Stanislav, Singh, Vinayak, Polčicová, Alica, Baráth, Peter, Barrio, María Belén, Lagrange, Sophie, Leblanc, Véronique, Nacy, Carol A., Mizrahi, Valerie, Mikušová, Katarína
Publicado no Antimicrob Agents Chemother (2017)

Decaprenylphosphoryl Arabinofuranose, the Donor of the d-Arabinofuranosyl Residues of Mycobacterial Arabinan, Is Formed via a Two-Step Epimerization of Decaprenylphosphoryl Ribose

Por Mikušová, Katarína, Huang, Hairong, Yagi, Tetsuya, Holsters, Marcelle, Vereecke, Danny, D'Haeze, Wim, Scherman, Michael S., Brennan, Patrick J., McNeil, Michael R., Crick, Dean C.
Publicado em 2005

Drugging the Folate Pathway in Mycobacterium Tuberculosis: The Role of Multi-Targeting Agents

Por Hajian, Behnoush, Scocchera, Eric, Shoen, Carolyn, Krucinska, Jolanta, Viswanathan, Kishore, G-Dayanandan, Narendran, Erlandsen, Heidi, Estrada, Alexavier, Mikušová, Katarína, Korduláková, Jana, Cynamon, Michael, Wright, Dennis
Publicado no Cell Chem Biol (2019)

Fragment-Based Design of Mycobacterium tuberculosis InhA Inhibitors

Por Sabbah, Mohamad, Mendes, Vitor, Vistal, Robert G., Dias, David M. G., Záhorszká, Monika, Mikušová, Katarína, Korduláková, Jana, Coyne, Anthony G., Blundell, Tom L., Abell, Chris
Publicado no J Med Chem (2020)

Correction to Fragment-Based Design of Mycobacterium tuberculosis InhA Inhibitors

Por Sabbah, Mohamad, Mendes, Vitor, Vistal, Robert G., Dias, David M. G., Záhorszká, Monika, Mikušová, Katarína, Korduláková, Jana, Coyne, Anthony G., Blundell, Tom L., Abell, Chris
Publicado no J Med Chem (2020)

Design, Syntheses, and Anti-TB Activity of 1,3-Benzothiazinone Azide and Click Chemistry Products Inspired by BTZ043

Por Tiwari, Rohit, Miller, Patricia A., Chiarelli, Laurent R., Mori, Giorgia, Šarkan, Michal, Centárová, Ivana, Cho, Sanghyun, Mikušová, Katarína, Franzblau, Scott G., Oliver, Allen G., Miller, Marvin J.
Publicado no ACS Med Chem Lett (2016)

Biosynthetic Origin of the Galactosamine Substituent of Arabinogalactan in Mycobacterium tuberculosis

Por Škovierová, Henrieta, Larrouy-Maumus, Gérald, Pham, Ha, Belanová, Martina, Barilone, Nathalie, DasGupta, Arunava, Mikušová, Katarina, Gicquel, Brigitte, Gilleron, Martine, Brennan, Patrick. J., Puzo, Germain, Nigou, Jérôme, Jackson, Mary
Publicado em 2010

The 8-Pyrrole-Benzothiazinones Are Noncovalent Inhibitors of DprE1 from Mycobacterium tuberculosis

Por Makarov, Vadim, Neres, João, Hartkoorn, Ruben C., Ryabova, Olga B., Kazakova, Elena, Šarkan, Michal, Huszár, Stanislav, Piton, Jérémie, Kolly, Gaëlle S., Vocat, Anthony, Conroy, Trent M., Mikušová, Katarína, Cole, Stewart T.
Publicado no Antimicrob Agents Chemother (2015)

Synthetic UDP-furanoses as potent inhibitors of mycobacterial galactan biogenesis

Por Peltier, Pauline, Beláňová, Martina, Dianišková, Petronela, Zhou, Ruokun, Zheng, Ruixiang Blake, Pearcey, Jean A., Joe, Maju, Brennan, Patrick J., Nugier-Chauvin, Caroline, Ferrières, Vincent, Lowary, Todd L., Daniellou, Richard, Mikušová, Katarína
Publicado em 2010

Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA

Por Albesa-Jové, David, Svetlíková, Zuzana, Tersa, Montse, Sancho-Vaello, Enea, Carreras-González, Ana, Bonnet, Pascal, Arrasate, Pedro, Eguskiza, Ander, Angala, Shiva K., Cifuente, Javier O., Korduláková, Jana, Jackson, Mary, Mikušová, Katarína, Guerin, Marcelo E.
Publicado no Nat Commun (2016)

A Small Multidrug Resistance-like Transporter Involved in the Arabinosylation of Arabinogalactan and Lipoarabinomannan in Mycobacteria

Por Larrouy-Maumus, Gérald, Škovierová, Henrieta, Dhouib, Rabeb, Angala, Shiva Kumar, Zuberogoitia, Sophie, Pham, Ha, Villela, Anne Drumond, Mikušová, Katarina, Noguera, Audrey, Gilleron, Martine, Valentínová, Lucia, Korduláková, Jana, Brennan, Patrick. J., Puzo, Germain, Nigou, Jérôme, Jackson, Mary
Publicado em 2012

An ethA-ethR-Deficient Mycobacterium bovis BCG Mutant Displays Increased Adherence to Mammalian Cells and Greater Persistence In Vivo, Which Correlate with Altered Mycolic Acid Com...

Por Ang, Michelle Lay Teng, Siti, Zarina Zainul Rahim, Shui, Guanghou, Dianišková, Petronela, Madacki, Jan, Lin, Wenwei, Koh, Vanessa Hui Qi, Martinez Gomez, Julia Maria, Sudarkodi, Sukumar, Bendt, Anne, Wenk, Markus, Mikušová, Katarína, Korduláková, Jana, Pethe, Kevin, Alonso, Sylvie
Publicado em 2014