Design, Syntheses, and Anti-TB Activity of 1,3-Benzothiazinone Azide and Click Chemistry Products Inspired by BTZ043

[Image: see text] Electron deficient nitroaromatic compounds such as BTZ043 and its closest congener, PBTZ169, and related agents are a promising new class of anti-TB compounds. Herein we report the design and syntheses of 1,3-benzothiazinone azide (BTZ-N(3)) and related click chemistry products bas...

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Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Tiwari, Rohit, Miller, Patricia A., Chiarelli, Laurent R., Mori, Giorgia, Šarkan, Michal, Centárová, Ivana, Cho, Sanghyun, Mikušová, Katarína, Franzblau, Scott G., Oliver, Allen G., Miller, Marvin J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2016
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4789662/
https://ncbi.nlm.nih.gov/pubmed/26985313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.5b00424
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