Application of a resazurin-based high-throughput screening assay for the identification and progression of new treatments for human African trypanosomiasis

Por Bowling, Tana, Mercer, Luke, Don, Robert, Jacobs, Robert, Nare, Bakela
Publicado em 2012

2,4-Diaminopyrimidines as Potent Inhibitors of Trypanosoma brucei and Identification of Molecular Targets by a Chemical Proteomics Approach

Por Mercer, Luke, Bowling, Tana, Perales, Joe, Freeman, Jennifer, Nguyen, Tien, Bacchi, Cyrus, Yarlett, Nigel, Don, Robert, Jacobs, Robert, Nare, Bakela
Publicado em 2011

Pharmacokinetics and pharmacodynamics utilizing unbound target tissue exposure as part of a disposition-based rationale for lead optimization of benzoxaboroles in the treatment of...

Por WRING, STEPHEN, GAUKEL, ERIC, NARE, BAKELA, JACOBS, ROBERT, BEAUDET, BETH, BOWLING, TANA, MERCER, LUKE, BACCHI, CYRUS, YARLETT, NIGEL, RANDOLPH, RYAN, PARHAM, ROBIN, REWERTS, CINDY, PLATNER, JACOB, DON, ROBERT
Publicado em 2014

Discovery of Novel Orally Bioavailable Oxaborole 6-Carboxamides That Demonstrate Cure in a Murine Model of Late-Stage Central Nervous System African Trypanosomiasis

Por Nare, Bakela, Wring, Stephen, Bacchi, Cyrus, Beaudet, Beth, Bowling, Tana, Brun, Reto, Chen, Daitao, Ding, Charles, Freund, Yvonne, Gaukel, Eric, Hussain, Ali, Jarnagin, Kurt, Jenks, Matthew, Kaiser, Marcel, Mercer, Luke, Mejia, Elena, Noe, Andy, Orr, Matt, Parham, Robin, Plattner, Jacob, Randolph, Ryan, Rattendi, Donna, Rewerts, Cindy, Sligar, Jessica, Yarlett, Nigel, Don, Robert, Jacobs, Robert
Publicado em 2010

SCYX-7158, an Orally-Active Benzoxaborole for the Treatment of Stage 2 Human African Trypanosomiasis

Por Jacobs, Robert T., Nare, Bakela, Wring, Stephen A., Orr, Matthew D., Chen, Daitao, Sligar, Jessica M., Jenks, Matthew X., Noe, Robert A., Bowling, Tana S., Mercer, Luke T., Rewerts, Cindy, Gaukel, Eric, Owens, Jennifer, Parham, Robin, Randolph, Ryan, Beaudet, Beth, Bacchi, Cyrus J., Yarlett, Nigel, Plattner, Jacob J., Freund, Yvonne, Ding, Charles, Akama, Tsutomu, Zhang, Y.-K., Brun, Reto, Kaiser, Marcel, Scandale, Ivan, Don, Robert
Publicado em 2011

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

Por Van Voorhis, Wesley C., Adams, John H., Adelfio, Roberto, Ahyong, Vida, Akabas, Myles H., Alano, Pietro, Alday, Aintzane, Alemán Resto, Yesmalie, Alsibaee, Aishah, Alzualde, Ainhoa, Andrews, Katherine T., Avery, Simon V., Avery, Vicky M., Ayong, Lawrence, Baker, Mark, Baker, Stephen, Ben Mamoun, Choukri, Bhatia, Sangeeta, Bickle, Quentin, Bounaadja, Lotfi, Bowling, Tana, Bosch, Jürgen, Boucher, Lauren E., Boyom, Fabrice F., Brea, Jose, Brennan, Marian, Burton, Audrey, Caffrey, Conor R., Camarda, Grazia, Carrasquilla, Manuela, Carter, Dee, Belen Cassera, Maria, Chih-Chien Cheng, Ken, Chindaudomsate, Worathad, Chubb, Anthony, Colon, Beatrice L., Colón-López, Daisy D., Corbett, Yolanda, Crowther, Gregory J., Cowan, Noemi, D’Alessandro, Sarah, Le Dang, Na, Delves, Michael, DeRisi, Joseph L., Du, Alan Y., Duffy, Sandra, Abd El-Salam El-Sayed, Shimaa, Ferdig, Michael T., Fernández Robledo, José A., Fidock, David A., Florent, Isabelle, Fokou, Patrick V. T., Galstian, Ani, Gamo, Francisco Javier, Gokool, Suzanne, Gold, Ben, Golub, Todd, Goldgof, Gregory M., Guha, Rajarshi, Guiguemde, W. Armand, Gural, Nil, Guy, R. Kiplin, Hansen, Michael A. E., Hanson, Kirsten K., Hemphill, Andrew, Hooft van Huijsduijnen, Rob, Horii, Takaaki, Horrocks, Paul, Hughes, Tyler B., Huston, Christopher, Igarashi, Ikuo, Ingram-Sieber, Katrin, Itoe, Maurice A., Jadhav, Ajit, Naranuntarat Jensen, Amornrat, Jensen, Laran T., Jiang, Rays H. Y., Kaiser, Annette, Keiser, Jennifer, Ketas, Thomas, Kicka, Sebastien, Kim, Sunyoung, Kirk, Kiaran, Kumar, Vidya P., Kyle, Dennis E., Lafuente, Maria Jose, Landfear, Scott, Lee, Nathan, Lee, Sukjun, Lehane, Adele M., Li, Fengwu, Little, David, Liu, Liqiong, Llinás, Manuel, Loza, Maria I., Lubar, Aristea, Lucantoni, Leonardo, Lucet, Isabelle, Maes, Louis, Mancama, Dalu, Mansour, Nuha R., March, Sandra, McGowan, Sheena, Medina Vera, Iset, Meister, Stephan, Mercer, Luke, Mestres, Jordi, Mfopa, Alvine N., Misra, Raj N., Moon, Seunghyun, Moore, John P., Morais Rodrigues da Costa, Francielly, Müller, Joachim, Muriana, Arantza, Nakazawa Hewitt, Stephen, Nare, Bakela, Nathan, Carl, Narraidoo, Nathalie, Nawaratna, Sujeevi, Ojo, Kayode K., Ortiz, Diana, Panic, Gordana, Papadatos, George, Parapini, Silvia, Patra, Kailash, Pham, Ngoc, Prats, Sarah, Plouffe, David M., Poulsen, Sally-Ann, Pradhan, Anupam, Quevedo, Celia, Quinn, Ronald J., Rice, Christopher A., Abdo Rizk, Mohamed, Ruecker, Andrea, St. Onge, Robert, Salgado Ferreira, Rafaela, Samra, Jasmeet, Robinett, Natalie G., Schlecht, Ulrich, Schmitt, Marjorie, Silva Villela, Filipe, Silvestrini, Francesco, Sinden, Robert, Smith, Dennis A., Soldati, Thierry, Spitzmüller, Andreas, Stamm, Serge Maximilian, Sullivan, David J., Sullivan, William, Suresh, Sundari, Suzuki, Brian M., Suzuki, Yo, Swamidass, S. Joshua, Taramelli, Donatella, Tchokouaha, Lauve R. Y., Theron, Anjo, Thomas, David, Tonissen, Kathryn F., Townson, Simon, Tripathi, Abhai K., Trofimov, Valentin, Udenze, Kenneth O., Ullah, Imran, Vallieres, Cindy, Vigil, Edgar, Vinetz, Joseph M., Voong Vinh, Phat, Vu, Hoan, Watanabe, Nao-aki, Weatherby, Kate, White, Pamela M., Wilks, Andrew F., Winzeler, Elizabeth A., Wojcik, Edward, Wree, Melanie, Wu, Wesley, Yokoyama, Naoaki, Zollo, Paul H. A., Abla, Nada, Blasco, Benjamin, Burrows, Jeremy, Laleu, Benoît, Leroy, Didier, Spangenberg, Thomas, Wells, Timothy, Willis, Paul A.
Publicado no PLoS Pathog (2016)