Application of a resazurin-based high-throughput screening assay for the identification and progression of new treatments for human African trypanosomiasis

Por Bowling, Tana, Mercer, Luke, Don, Robert, Jacobs, Robert, Nare, Bakela
Publicado em 2012

A Review: The Current In Vivo Models for the Discovery and Utility of New Anti-leishmanial Drugs Targeting Cutaneous Leishmaniasis

Por Mears, Emily Rose, Modabber, Farrokh, Don, Robert, Johnson, George E.
Publicado no PLoS Negl Trop Dis (2015)

To Fully Tackle the Gang of Four, Needs-Driven R & D Is Essential

Por Torreele, Els, Royce, Catherine, Don, Robert, Sevcsik, Ann-Marie, Croft, Simon
Publicado em 2006

Potential Drug Development Candidates for Human Soil-Transmitted Helminthiases

Por Olliaro, Piero, Seiler, Jürg, Kuesel, Annette, Horton, John, Clark, Jeffrey N., Don, Robert, Keiser, Jennifer
Publicado em 2011

Synergy Testing of FDA-Approved Drugs Identifies Potent Drug Combinations against Trypanosoma cruzi

Por Planer, Joseph D., Hulverson, Matthew A., Arif, Jennifer A., Ranade, Ranae M., Don, Robert, Buckner, Frederick S.
Publicado em 2014

New, Improved Treatments for Chagas Disease: From the R&D Pipeline to the Patients

Por Ribeiro, Isabela, Sevcsik, Ann-Marie, Alves, Fabiana, Diap, Graciela, Don, Robert, Harhay, Michael O., Chang, Shing, Pecoul, Bernard
Publicado em 2009

2,4-Diaminopyrimidines as Potent Inhibitors of Trypanosoma brucei and Identification of Molecular Targets by a Chemical Proteomics Approach

Por Mercer, Luke, Bowling, Tana, Perales, Joe, Freeman, Jennifer, Nguyen, Tien, Bacchi, Cyrus, Yarlett, Nigel, Don, Robert, Jacobs, Robert, Nare, Bakela
Publicado em 2011

Pharmacokinetics and pharmacodynamics utilizing unbound target tissue exposure as part of a disposition-based rationale for lead optimization of benzoxaboroles in the treatment of...

Por WRING, STEPHEN, GAUKEL, ERIC, NARE, BAKELA, JACOBS, ROBERT, BEAUDET, BETH, BOWLING, TANA, MERCER, LUKE, BACCHI, CYRUS, YARLETT, NIGEL, RANDOLPH, RYAN, PARHAM, ROBIN, REWERTS, CINDY, PLATNER, JACOB, DON, ROBERT
Publicado em 2014

Discovery of Novel Orally Bioavailable Oxaborole 6-Carboxamides That Demonstrate Cure in a Murine Model of Late-Stage Central Nervous System African Trypanosomiasis

Por Nare, Bakela, Wring, Stephen, Bacchi, Cyrus, Beaudet, Beth, Bowling, Tana, Brun, Reto, Chen, Daitao, Ding, Charles, Freund, Yvonne, Gaukel, Eric, Hussain, Ali, Jarnagin, Kurt, Jenks, Matthew, Kaiser, Marcel, Mercer, Luke, Mejia, Elena, Noe, Andy, Orr, Matt, Parham, Robin, Plattner, Jacob, Randolph, Ryan, Rattendi, Donna, Rewerts, Cindy, Sligar, Jessica, Yarlett, Nigel, Don, Robert, Jacobs, Robert
Publicado em 2010

SCYX-7158, an Orally-Active Benzoxaborole for the Treatment of Stage 2 Human African Trypanosomiasis

Por Jacobs, Robert T., Nare, Bakela, Wring, Stephen A., Orr, Matthew D., Chen, Daitao, Sligar, Jessica M., Jenks, Matthew X., Noe, Robert A., Bowling, Tana S., Mercer, Luke T., Rewerts, Cindy, Gaukel, Eric, Owens, Jennifer, Parham, Robin, Randolph, Ryan, Beaudet, Beth, Bacchi, Cyrus J., Yarlett, Nigel, Plattner, Jacob J., Freund, Yvonne, Ding, Charles, Akama, Tsutomu, Zhang, Y.-K., Brun, Reto, Kaiser, Marcel, Scandale, Ivan, Don, Robert
Publicado em 2011