FAS-Associated Factor 1 (FAF1): diverse functions and implications for oncogenesis

Por Menges, Craig W., Altomare, Deborah A., Testa, Joseph R.
Publicado em 2009

A Phosphotyrosine Proteomic Screen Identifies Multiple Tyrosine Kinase Signaling Pathways Aberrantly Activated in Malignant Mesothelioma

Por Menges, Craig W., Chen, Yibai, Mossman, Brooke T., Chernoff, Jonathan, Yeung, Anthony T., Testa, Joseph R.
Publicado em 2010

Up Regulation of DLX5 Promotes Ovarian Cancer Cell Proliferation by Enhancing IRS-2-AKT Signaling

Por Tan, Yinfei, Cheung, Mitchell, Pei, Jianming, Menges, Craig W., Godwin, Andrew K., Testa, Joseph R.
Publicado em 2010

Group I p21-Activated Kinases (PAKs) Promote Tumor Cell Proliferation and Survival Through the AKT1 and Raf-MAPK Pathways

Por Menges, Craig W., Sementino, Eleonora, Talarchek, Jacqueline, Xu, Jinfei, Chernoff, Jonathan, Peterson, Jeffrey R., Testa, Joseph R.
Publicado em 2012

Activated TNF-α/NF-κB signaling via down-regulation of Fas-associated factor 1 in asbestos-induced mesotheliomas from Arf knockout mice

Por Altomare, Deborah A., Menges, Craig W., Pei, Jianming, Zhang, Lili, Skele-Stump, Kristine L., Carbone, Michele, Kane, Agnes B., Testa, Joseph R.
Publicado em 2009

Flaxseed lignans enriched in secoisolariciresinol diglucoside prevent acute asbestos-induced peritoneal inflammation in mice

Por Pietrofesa, Ralph A., Velalopoulou, Anastasia, Arguiri, Evguenia, Menges, Craig W., Testa, Joseph R., Hwang, Wei-Ting, Albelda, Steven M., Christofidou-Solomidou, Melpo
Publicado no Carcinogenesis (2016)

Bap1 is a bona fide tumor suppressor: genetic evidence from mouse models carrying heterozygous germline Bap1 mutations

Por Kadariya, Yuwaraj, Cheung, Mitchell, Xu, Jinfei, Pei, Jianming, Sementino, Eleonora, Menges, Craig W., Cai, Kathy Q., Rauscher, Frank J., Klein-Szanto, Andres J., Testa, Joseph R.
Publicado no Cancer Res (2016)

Inflammation-Related IL-1β/IL-1R Signaling Promotes the Development of Asbestos-Induced Malignant Mesothelioma

Por Kadariya, Yuwaraj, Menges, Craig W., Talarchek, Jacqueline, Cai, Kathy Q., Klein-Szanto, Andres J., Pietrofesa, Ralph A., Christofidou-Solomidou, Melpo, Cheung, Mitchell, Mossman, Brooke T., Shukla, Arti, Testa, Joseph R.
Publicado no Cancer Prev Res (Phila) (2016)

Losses of Both Products of the Cdkn2a/Arf Locus Contribute to Asbestos-Induced Mesothelioma Development and Cooperate to Accelerate Tumorigenesis

Por Altomare, Deborah A., Menges, Craig W., Xu, Jinfei, Pei, Jianming, Zhang, Lili, Tadevosyan, Ara, Neumann-Domer, Erin, Liu, Zemin, Carbone, Michele, Chudoba, Ilse, Klein-Szanto, Andres J., Testa, Joseph R.
Publicado em 2011

Germline Mutation of Bap1 Accelerates Development of Asbestos-Induced Malignant Mesothelioma

Por Xu, Jinfei, Kadariya, Yuwaraj, Cheung, Mitchell, Pei, Jianming, Talarchek, Jacqueline, Sementino, Eleonora, Tan, Yinfei, Menges, Craig W., Cai, Kathy Q., Litwin, Samuel, Peng, Hongzhuang, Karar, Jayashree, Rauscher, Frank J., Testa, Joseph R.
Publicado em 2014

Tumor Suppressor Alterations Cooperate to Drive Aggressive Mesotheliomas with Enriched Cancer Stem Cells via a p53-miR34a-c-Met Axis

Por Menges, Craig W., Kadariya, Yuwaraj, Altomare, Deborah, Talarchek, Jacqueline, Neumann-Domer, Erin, Wu, Yue, Xiao, Guang-Hui, Shapiro, Irina M., Kolev, Vihren N., Pachter, Jonathan A., Klein-Szanto, Andres J., Testa, Joseph R.
Publicado em 2013

Haploinsufficiency in tumor predisposition syndromes: altered genomic transcription in morphologically normal cells heterozygous for VHL or TSC mutation

Por Peri, Suraj, Caretti, Elena, Tricarico, Rossella, Devarajan, Karthik, Cheung, Mitchell, Sementino, Eleonora, Menges, Craig W., Nicolas, Emmanuelle, Vanderveer, Lisa A., Howard, Sharon, Conrad, Peggy, Crowell, James A., Campbell, Kerry S., Ross, Eric A., Godwin, Andrew K., Yeung, Anthony T., Clapper, Margie L., Uzzo, Robert G., Henske, Elizabeth P., Ricketts, Christopher J., Vocke, Cathy D., Linehan, W. Marston, Testa, Joseph R., Bellacosa, Alfonso, Kopelovich, Levy, Knudson, Alfred G.
Publicado no Oncotarget (2016)