The Contribution of Experimental in vivo Models to Understanding the Mechanisms of Adaptation to Mechanical Loading in Bone

ανά Meakin, Lee B., Price, Joanna S., Lanyon, Lance E.
Έκδοση 2014

Age-Related Impairment of Bones' Adaptive Response to Loading in Mice Is Associated With Sex-Related Deficiencies in Osteoblasts but No Change in Osteocytes†

ανά Meakin, Lee B, Galea, Gabriel L, Sugiyama, Toshihiro, Lanyon, Lance E, Price, Joanna S
Τόπος έκδοσης J Bone Miner Res (2014)

Exercise does not enhance aged bone's impaired response to artificial loading in C57Bl/6 mice

ανά Meakin, Lee B., Udeh, Chinedu, Galea, Gabriel L., Lanyon, Lance E., Price, Joanna S.
Τόπος έκδοσης Bone (2015)

Bones' Adaptive Response to Mechanical Loading Is Essentially Linear Between the Low Strains Associated With Disuse and the High Strains Associated With the Lamellar/Woven Bone Tra...

ανά Sugiyama, Toshihiro, Meakin, Lee B, Browne, William J, Galea, Gabriel L, Price, Joanna S, Lanyon, Lance E
Έκδοση 2012

Male mice housed in groups engage in frequent fighting and show a lower response to additional bone loading than females or individually housed males that do not fight

ανά Meakin, Lee B., Sugiyama, Toshihiro, Galea, Gabriel L., Browne, William J., Lanyon, Lance E., Price, Joanna S.
Έκδοση 2013

Quantification of Alterations in Cortical Bone Geometry Using Site Specificity Software in Mouse models of Aging and the Responses to Ovariectomy and Altered Loading

ανά Galea, Gabriel L., Hannuna, Sion, Meakin, Lee B., Delisser, Peter J., Lanyon, Lance E., Price, Joanna S.
Τόπος έκδοσης Front Endocrinol (Lausanne) (2015)

Colored Indicator Undergloves Increase the Detection of Glove Perforations by Surgeons During Small Animal Orthopedic Surgery: A Randomized Controlled Trial

ανά Meakin, Lee B., Gilman, Oliver P., Parsons, Kevin J., Burton, Neil J., Langley‐Hobbs, Sorrel J.
Τόπος έκδοσης Vet Surg (2016)

Cortical Thickness Adaptive Response to Mechanical Loading Depends on Periosteal Position and Varies Linearly With Loading Magnitude

ανά Miller, Corey J., Trichilo, Silvia, Pickering, Edmund, Martelli, Saulo, Delisser, Peter, Meakin, Lee B., Pivonka, Peter
Τόπος έκδοσης Front Bioeng Biotechnol (2021)

Sost down-regulation by mechanical strain in human osteoblastic cells involves PGE2 signaling via EP4

ανά Galea, Gabriel L., Sunters, Andrew, Meakin, Lee B., Zaman, Gul, Sugiyama, Toshihiro, Lanyon, Lance E., Price, Joanna S.
Έκδοση 2011

Wnt16 Is Associated with Age-Related Bone Loss and Estrogen Withdrawal in Murine Bone

ανά Todd, Henry, Galea, Gabriel L., Meakin, Lee B., Delisser, Peter J., Lanyon, Lance E., Windahl, Sara H., Price, Joanna S.
Τόπος έκδοσης PLoS One (2015)

Electrosurgery reduces blood loss and immediate postoperative inflammation compared to cold instruments for midline celiotomy in dogs: A randomized controlled trial

ανά Meakin, Lee B., Murrell, Jo C., Doran, Ivan C. P., Knowles, Toby G., Tivers, Michael S., Chanoit, Guillaume P. A.
Τόπος έκδοσης Vet Surg (2017)

Old age and the associated impairment of bones' adaptation to loading are associated with transcriptomic changes in cellular metabolism, cell-matrix interactions and the cell cycle

ανά Galea, Gabriel L., Meakin, Lee B., Harris, Marie A., Delisser, Peter J., Lanyon, Lance E., Harris, Stephen E., Price, Joanna S.
Τόπος έκδοσης Gene (2017)

Protein Kinase Cα (PKCα) Regulates Bone Architecture and Osteoblast Activity

ανά Galea, Gabriel L., Meakin, Lee B., Williams, Christopher M., Hulin-Curtis, Sarah L., Lanyon, Lance E., Poole, Alastair W., Price, Joanna S.
Έκδοση 2014

Parathyroid hormone's enhancement of bones' osteogenic response to loading is affected by ageing in a dose- and time-dependent manner

ανά Meakin, Lee B, Todd, Henry, Delisser, Peter J, Galea, Gabriel L, Moustafa, Alaa, Lanyon, Lance E, Windahl, Sara H, Price, Joanna S
Τόπος έκδοσης Bone (2017)

Spinal Deformity in Aged Zebrafish Is Accompanied by Degenerative Changes to Their Vertebrae that Resemble Osteoarthritis

ανά Hayes, Anthony J., Reynolds, Scott, Nowell, Mari A., Meakin, Lee B., Habicher, Judith, Ledin, Johan, Bashford, Andrew, Caterson, Bruce, Hammond, Chrissy L.
Έκδοση 2013

Deletion of P58(IPK), the Cellular Inhibitor of the Protein Kinases PKR and PERK, Causes Bone Changes and Joint Degeneration in Mice

ανά Gilbert, Sophie J., Meakin, Lee B., Bonnet, Cleo S., Nowell, Mari A., Ladiges, Warren C., Morton, John, Duance, Victor C., Mason, Deborah J.
Έκδοση 2014

Risedronate does not reduce mechanical loading-related increases in cortical and trabecular bone mass in mice

ανά Sugiyama, Toshihiro, Meakin, Lee B., Galea, Gabriel L., Jackson, Brendan F., Lanyon, Lance E., Ebetino, Frank H., Russell, R. Graham G., Price, Joanna S.
Έκδοση 2011

Estrogen Receptor α Mediates Proliferation of Osteoblastic Cells Stimulated by Estrogen and Mechanical Strain, but Their Acute Down-regulation of the Wnt Antagonist Sost Is Mediate...

ανά Galea, Gabriel L., Meakin, Lee B., Sugiyama, Toshihiro, Zebda, Noureddine, Sunters, Andrew, Taipaleenmaki, Hanna, Stein, Gary S., van Wijnen, Andre J., Lanyon, Lance E., Price, Joanna S.
Έκδοση 2013

Planar Cell Polarity Aligns Osteoblast Division in Response to Substrate Strain

ανά Galea, Gabriel L, Meakin, Lee B, Savery, Dawn, Taipaleenmaki, Hanna, Delisser, Peter, Stein, Gary S, Copp, Andrew J, van Wijnen, Andre J, Lanyon, Lance E, Price, Joanna S
Τόπος έκδοσης J Bone Miner Res (2015)

Mechanical strain-mediated reduction in RANKL expression is associated with RUNX2 and BRD2

ανά Galea, Gabriel L., Paradise, Christopher R., Meakin, Lee B., Camilleri, Emily T., Taipaleenmaki, Hanna, Stein, Gary S., Lanyon, Lance E., Price, Joanna S., van Wijnen, Andre J., Dudakovic, Amel
Τόπος έκδοσης Gene X (2020)