Parathyroid hormone's enhancement of bones' osteogenic response to loading is affected by ageing in a dose- and time-dependent manner

Decreased effectiveness of bones' adaptive response to mechanical loading contributes to age-related bone loss. In young mice, intermittent administration of parathyroid hormone (iPTH) at 20–80 μg/kg/day interacts synergistically with artificially applied loading to increase bone mass. Here we...

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Detalhes bibliográficos
Publicado no:Bone
Main Authors: Meakin, Lee B, Todd, Henry, Delisser, Peter J, Galea, Gabriel L, Moustafa, Alaa, Lanyon, Lance E, Windahl, Sara H, Price, Joanna S
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2017
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Full Length Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5404907/
https://ncbi.nlm.nih.gov/pubmed/28249797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2017.02.009
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