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Protein Kinase Cα (PKCα) Regulates Bone Architecture and Osteoblast Activity

Bones' strength is achieved and maintained through adaptation to load bearing. The role of the protein kinase PKCα in this process has not been previously reported. However, we observed a phenotype in the long bones of Prkca(−/−) female but not male mice, in which bone tissue progressively inva...

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Detalhes bibliográficos
Main Authors: Galea, Gabriel L., Meakin, Lee B., Williams, Christopher M., Hulin-Curtis, Sarah L., Lanyon, Lance E., Poole, Alastair W., Price, Joanna S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162157/
https://ncbi.nlm.nih.gov/pubmed/25070889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.580365
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