Protein Kinase Cα (PKCα) Regulates Bone Architecture and Osteoblast Activity

Bones' strength is achieved and maintained through adaptation to load bearing. The role of the protein kinase PKCα in this process has not been previously reported. However, we observed a phenotype in the long bones of Prkca(−/−) female but not male mice, in which bone tissue progressively inva...

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Autors principals: Galea, Gabriel L., Meakin, Lee B., Williams, Christopher M., Hulin-Curtis, Sarah L., Lanyon, Lance E., Poole, Alastair W., Price, Joanna S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162157/
https://ncbi.nlm.nih.gov/pubmed/25070889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.580365
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