Autism spectrum disorder: prospects for treatment using gene therapy

le Benger, Matthew, Kinali, Maria, Mazarakis, Nicholas D.
Foilsithe in Mol Autism (2018)

The Interaction of Genetic Mutations in PARK2 and FA2H Causes a Novel Phenotype in a Case of Childhood-Onset Movement Disorder

le Benger, Matthew, Mankad, Kshitij, Proukakis, Christos, Mazarakis, Nicholas D., Kinali, Maria
Foilsithe in Front Neurol (2019)

α CAR IGF‐1 vector targeting of motor neurons ameliorates disease progression in ALS mice

le Eleftheriadou, Ioanna, Manolaras, Ioannis, Irvine, Elaine E., Dieringer, Michael, Trabalza, Antonio, Mazarakis, Nicholas D.
Foilsithe in Ann Clin Transl Neurol (2016)

Dual systemic tumor targeting with ligand-directed phage and Grp78 promoter induces tumor regression

le Kia, Azadeh, Przystal, Justyna M., Nianiaris, Nastasia, Mazarakis, Nicholas D., Mintz, Paul J., Hajitou, Amin
Foilsithe 2012

A Heterotypic Bystander Effect for Tumor Cell Killing after AAVP-mediated Vascular-targeted Suicide Gene Transfer

le Trepel, Martin, Stoneham, Charlotte A., Eleftherohorinou, Hariklia, Mazarakis, Nicholas D., Pasqualini, Renata, Arap, Wadih, Hajitou, Amin
Foilsithe 2009

Enhanced Central Nervous System Transduction with Lentiviral Vectors Pseudotyped with RVG/HIV-1gp41 Chimeric Envelope Glycoproteins

le Trabalza, Antonio, Eleftheriadou, Ioanna, Sgourou, Argyro, Liao, Ting-Yi, Patsali, Petros, Lee, Heyne, Mazarakis, Nicholas D.
Foilsithe 2014

Persistent elevation of intrathecal pro-inflammatory cytokines leads to multiple sclerosis-like cortical demyelination and neurodegeneration

le James, Rachel E., Schalks, Renee, Browne, Eleanor, Eleftheriadou, Ioanna, Munoz, Carmen Picon, Mazarakis, Nicholas D., Reynolds, Richard
Foilsithe in Acta Neuropathol Commun (2020)

Rabies Virus Envelope Glycoprotein Targets Lentiviral Vectors to the Axonal Retrograde Pathway in Motor Neurons

le Hislop, James N., Islam, Tarin A., Eleftheriadou, Ioanna, Carpentier, David C. J., Trabalza, Antonio, Parkinson, Michael, Schiavo, Giampietro, Mazarakis, Nicholas D.
Foilsithe 2014

Neuron-specific activation of necroptosis signaling in multiple sclerosis cortical grey matter

le Picon, Carmen, Jayaraman, Anusha, James, Rachel, Beck, Catriona, Gallego, Patricia, Witte, Maarten E., van Horssen, Jack, Mazarakis, Nicholas D., Reynolds, Richard
Foilsithe in Acta Neuropathol (2021)

Dose-dependent Neuroprotection of VEGF(165) in Huntington's Disease Striatum

le Ellison, Stuart M, Trabalza, Antonio, Tisato, Veronica, Pazarentzos, Evangelos, Lee, Shirley, Papadaki, Vasiliki, Goniotaki, Despoina, Morgan, Sarah, Mirzaei, Nazanin, Mazarakis, Nicholas D
Foilsithe 2013

PPARγ-coactivator-1α gene transfer reduces neuronal loss and amyloid-β generation by reducing β-secretase in an Alzheimer’s disease model

le Katsouri, Loukia, Lim, Yau M., Blondrath, Katrin, Eleftheriadou, Ioanna, Lombardero, Laura, Birch, Amy M., Mirzaei, Nazanin, Irvine, Elaine E., Mazarakis, Nicholas D., Sastre, Magdalena
Foilsithe in Proc Natl Acad Sci U S A (2016)

Multicistronic Lentiviral Vector-Mediated Striatal Gene Transfer of Aromatic l-Amino Acid Decarboxylase, Tyrosine Hydroxylase, and GTP Cyclohydrolase I Induces Sustained Transgene...

le Azzouz, Mimoun, Martin-Rendon, Enca, Barber, Robert D., Mitrophanous, Kyriacos A., Carter, Emma E., Rohll, Jonathan B., Kingsman, Susan M., Kingsman, Alan J., Mazarakis, Nicholas D.
Foilsithe in J Neurosci (2002)

Neuroinflammation in the normal-appearing white matter (NAWM) of the multiple sclerosis brain causes abnormalities at the nodes of Ranvier

le Gallego-Delgado, Patricia, James, Rachel, Browne, Eleanor, Meng, Joanna, Umashankar, Swetha, Tan, Li, Picon, Carmen, Mazarakis, Nicholas D., Faisal, A. Aldo, Howell, Owain W., Reynolds, Richard
Foilsithe in PLoS Biol (2020)

Branched Chain Amino Acids Induce Apoptosis in Neural Cells without Mitochondrial Membrane Depolarization or Cytochrome c Release: Implications for Neurological Impairment Assoc...

le Jouvet, Philippe, Rustin, Pierre, Taylor, Deanna L., Pocock, Jennifer M., Felderhoff-Mueser, Ursula, Mazarakis, Nicholas D., Sarraf, Catherine, Joashi, Umesh, Kozma, Mary, Greenwood, Kirsty, Edwards, A. David, Mehmet, Huseyin
Foilsithe 2000

Lentivector-mediated SMN replacement in a mouse model of spinal muscular atrophy

le Azzouz, Mimoun, Le, Thanh, Ralph, G. Scott, Walmsley, Lucy, Monani, Umrao R., Lee, Debbie C.P., Wilkes, Fraser, Mitrophanous, Kyriacos A., Kingsman, Susan M., Burghes, Arthur H.M., Mazarakis, Nicholas D.
Foilsithe 2004

IκΒα inhibits apoptosis at the outer mitochondrial membrane independently of NF-κB retention

le Pazarentzos, Evangelos, Mahul-Mellier, Anne-Laure, Datler, Christoph, Chaisaklert, Wanwisa, Hwang, Ming-Shih, Kroon, Jan, Qize, Ding, Osborne, Foy, Al-Rubaish, Abdullah, Al-Ali, Amein, Mazarakis, Nicholas D, Aboagye, Eric O, Grimm, Stefan
Foilsithe in EMBO J (2014)

Familial amyotrophic lateral sclerosis is associated with a mutation in D-amino acid oxidase

le Mitchell, John, Paul, Praveen, Chen, Han-Jou, Morris, Alex, Payling, Miles, Falchi, Mario, Habgood, James, Panoutsou, Stefania, Winkler, Sabine, Tisato, Veronica, Hajitou, Amin, Smith, Bradley, Vance, Caroline, Shaw, Christopher, Mazarakis, Nicholas D., de Belleroche, Jacqueline
Foilsithe 2010

Cyclin-dependent-like kinase 5 is required for pain signaling in human sensory neurons and mouse models

le La Montanara, Paolo, Hervera, Arnau, Baltussen, Lucas, Hutson, Thomas H, Palmisano, Ilaria, De Virgiliis, Francesco, Kong, Guiping, Chadwick, Jessica, Gao, Yunan, Bartus, Katalin, Majid, Qasim A., Gorgoraptis, Nikos, Wong, Kingsley, Downs, Jenny, Pizzorusso, Tommaso, Ultanir, Sila, Leonard, Helen, Yu, Hongwei, Millar, David S, Istvan, Nagy, Mazarakis, Nicholas D, Giovanni, Simone Di
Foilsithe in Sci Transl Med (2020)

Meningeal inflammation in multiple sclerosis induces phenotypic changes in cortical microglia that differentially associate with neurodegeneration

le van Olst, Lynn, Rodriguez-Mogeda, Carla, Picon, Carmen, Kiljan, Svenja, James, Rachel E., Kamermans, Alwin, van der Pol, Susanne M. A., Knoop, Lydian, Michailidou, Iliana, Drost, Evelien, Franssen, Marc, Schenk, Geert J., Geurts, Jeroen J. G., Amor, Sandra, Mazarakis, Nicholas D., van Horssen, Jack, de Vries, Helga E., Reynolds, Richard, Witte, Maarten E.
Foilsithe in Acta Neuropathol (2021)