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Rabies Virus Envelope Glycoprotein Targets Lentiviral Vectors to the Axonal Retrograde Pathway in Motor Neurons

Rabies pseudotyped lentiviral vectors have great potential in gene therapy, not least because of their ability to transduce neurons following their distal axonal application. However, very little is known about the molecular processes that underlie their retrograde transport and cell transduction. U...

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Detalhes bibliográficos
Main Authors: Hislop, James N., Islam, Tarin A., Eleftheriadou, Ioanna, Carpentier, David C. J., Trabalza, Antonio, Parkinson, Michael, Schiavo, Giampietro, Mazarakis, Nicholas D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047386/
https://ncbi.nlm.nih.gov/pubmed/24753246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.549980
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