Enhanced Central Nervous System Transduction with Lentiviral Vectors Pseudotyped with RVG/HIV-1gp41 Chimeric Envelope Glycoproteins

To investigate the potential benefits which may arise from pseudotyping the HIV-1 lentiviral vector with its homologous gp41 envelope glycoprotein (GP) cytoplasmic tail (CT), we created chimeric RVG/HIV-1gp41 GPs composed of the extracellular and transmembrane sequences of RVG and either the full-le...

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Bibliografische gegevens
Hoofdauteurs: Trabalza, Antonio, Eleftheriadou, Ioanna, Sgourou, Argyro, Liao, Ting-Yi, Patsali, Petros, Lee, Heyne, Mazarakis, Nicholas D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2014
Onderwerpen:
Gene Delivery
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958067/
https://ncbi.nlm.nih.gov/pubmed/24371049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03376-13
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