Dose-dependent Neuroprotection of VEGF(165) in Huntington's Disease Striatum

Huntington's disease (HD) is a devastating neurodegenerative disorder caused by abnormal polyglutamine expansion in the huntingtin protein (Exp-Htt). Currently, there are no effective treatments for HD. We used bidirectional lentiviral transfer vectors to generate in vitro and in vivo models of...

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Detaylı Bibliyografya
Asıl Yazarlar: Ellison, Stuart M, Trabalza, Antonio, Tisato, Veronica, Pazarentzos, Evangelos, Lee, Shirley, Papadaki, Vasiliki, Goniotaki, Despoina, Morgan, Sarah, Mirzaei, Nazanin, Mazarakis, Nicholas D
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2013
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059596/
https://ncbi.nlm.nih.gov/pubmed/23799534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.132
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