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CalDAG-GEFI down-regulation in the striatum as a neuroprotective change in Huntington's disease
Huntingtin protein (Htt) is ubiquitously expressed, yet Huntington's disease (HD), a fatal neurologic disorder produced by expansion of an Htt polyglutamine tract, is characterized by neurodegeneration that occurs primarily in the striatum and cerebral cortex. Such discrepancies between sites o...
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| Autori principali: | , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2850620/ https://ncbi.nlm.nih.gov/pubmed/20147317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq055 |
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