VEGF-A(165)b Is an Endogenous Neuroprotective Splice Isoform of Vascular Endothelial Growth Factor A in Vivo and in Vitro

Vascular endothelial growth factor (VEGF) A is generated as two isoform families by alternative RNA splicing, represented by VEGF-A(165)a and VEGF-A(165)b. These isoforms have opposing actions on vascular permeability, angiogenesis, and vasodilatation. The proangiogenic VEGF-A(165)a isoform is neuro...

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Autors principals: Beazley-Long, Nicholas, Hua, Jing, Jehle, Thomas, Hulse, Richard P., Dersch, Rick, Lehrling, Christina, Bevan, Heather, Qiu, Yan, Lagrèze, Wolf A., Wynick, David, Churchill, Amanda J., Kehoe, Patrick, Harper, Steven J., Bates, David O., Donaldson, Lucy F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2013
Matèries:
Regular Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3763768/
https://ncbi.nlm.nih.gov/pubmed/23838428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.05.031
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