VEGF‐A(165)b protects against proteinuria in a mouse model with progressive depletion of all endogenous VEGF‐A splice isoforms from the kidney

KEY POINTS: Progressive depletion of all vascular endothelial growth factor A (VEGF‐A) splice isoforms from the kidney results in proteinuria and increased glomerular water permeability, which are both rescued by over‐expression of VEGF‐A(165)b only. VEGF‐A(165)b rescues the increase in glomerular b...

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Détails bibliographiques
Publié dans:J Physiol
Auteurs principaux: Stevens, Megan, Neal, Christopher R., Salmon, Andrew H. J., Bates, David O., Harper, Steven J., Oltean, Sebastian
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2017
Sujets:
Renal
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5621502/
https://ncbi.nlm.nih.gov/pubmed/28574576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP274481
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