VEGF‐A(165)b protects against proteinuria in a mouse model with progressive depletion of all endogenous VEGF‐A splice isoforms from the kidney

KEY POINTS: Progressive depletion of all vascular endothelial growth factor A (VEGF‐A) splice isoforms from the kidney results in proteinuria and increased glomerular water permeability, which are both rescued by over‐expression of VEGF‐A(165)b only. VEGF‐A(165)b rescues the increase in glomerular b...

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Foilsithe in:J Physiol
Main Authors: Stevens, Megan, Neal, Christopher R., Salmon, Andrew H. J., Bates, David O., Harper, Steven J., Oltean, Sebastian
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2017
Ábhair:
Renal
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5621502/
https://ncbi.nlm.nih.gov/pubmed/28574576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP274481
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