The endogenous anti-angiogenic VEGF isoform, VEGF(165)b inhibits human tumour growth in mice

Vascular endothelial growth factor-A is widely regarded as the principal stimulator of angiogenesis required for tumour growth. VEGF is generated as multiple isoforms of two families, the pro-angiogenic family generated by proximal splice site selection in the terminal exon, termed VEGF(xxx), and th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rennel, E S, Waine, E, Guan, H, Schüler, Y, Leenders, W, Woolard, J, Sugiono, M, Gillatt, D, Kleinerman, E S, Bates, D O, Harper, S J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2008
Schlagworte:
Translational Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2359649/
https://ncbi.nlm.nih.gov/pubmed/18349828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604309
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