A High-Throughput Cell-Based Method to Predict the Unbound Drug Fraction in the Brain

Por Mateus, André, Matsson, Pär, Artursson, Per
Publicado em 2014

Thermal proteome profiling: unbiased assessment of protein state through heat-induced stability changes

Por Mateus, André, Määttä, Tomi A., Savitski, Mikhail M.
Publicado no Proteome Sci (2017)

Improved predictions of time-dependent drug-drug interactions by determination of cytosolic drug concentrations

Por Filppula, Anne M., Parvizi, Rezvan, Mateus, André, Baranczewski, Pawel, Artursson, Per
Publicado no Sci Rep (2019)

Assessment of pharmacokinetic changes of meropenem during therapy in septic critically ill patients

Por Goncalves-Pereira, João, Silva, Nuno Elvas, Mateus, André, Pinho, Catarina, Povoa, Pedro
Publicado em 2014

Intracellular drug bioavailability: a new predictor of system dependent drug disposition

Por Mateus, André, Treyer, Andrea, Wegler, Christine, Karlgren, Maria, Matsson, Pär, Artursson, Per
Publicado no Sci Rep (2017)

Thermal proteome profiling in bacteria: probing protein state in vivo

Por Mateus, André, Bobonis, Jacob, Kurzawa, Nils, Stein, Frank, Helm, Dominic, Hevler, Johannes, Typas, Athanasios, Savitski, Mikhail M
Publicado no Mol Syst Biol (2018)

Thermal proteome profiling for interrogating protein interactions

Por Mateus, André, Kurzawa, Nils, Becher, Isabelle, Sridharan, Sindhuja, Helm, Dominic, Stein, Frank, Typas, Athanasios, Savitski, Mikhail M
Publicado no Mol Syst Biol (2020)

CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil

Por Almqvist, Helena, Axelsson, Hanna, Jafari, Rozbeh, Dan, Chen, Mateus, André, Haraldsson, Martin, Larsson, Andreas, Molina, Daniel Martinez, Artursson, Per, Lundbäck, Thomas, Nordlund, Pär
Publicado no Nat Commun (2016)

Prediction of intracellular exposure bridges the gap between target- and cell-based drug discovery

Por Mateus, André, Gordon, Laurie J., Wayne, Gareth J., Almqvist, Helena, Axelsson, Hanna, Seashore-Ludlow, Brinton, Treyer, Andrea, Matsson, Pär, Lundbäck, Thomas, West, Andy, Hann, Michael M., Artursson, Per
Publicado no Proc Natl Acad Sci U S A (2017)

Exploiting loss of heterozygosity for allele-selective colorectal cancer chemotherapy

Por Rendo, Veronica, Stoimenov, Ivaylo, Mateus, André, Sjöberg, Elin, Svensson, Richard, Gustavsson, Anna-Lena, Johansson, Lars, Ng, Adrian, OʼBrien, Casey, Giannakis, Marios, Artursson, Per, Nygren, Peter, Cheong, Ian, Sjöblom, Tobias
Publicado no Nat Commun (2020)

Pervasive Protein Thermal Stability Variation during the Cell Cycle

Por Becher, Isabelle, Andrés-Pons, Amparo, Romanov, Natalie, Stein, Frank, Schramm, Maike, Baudin, Florence, Helm, Dominic, Kurzawa, Nils, Mateus, André, Mackmull, Marie-Therese, Typas, Athanasios, Müller, Christoph W., Bork, Peer, Beck, Martin, Savitski, Mikhail M.
Publicado no Cell (2018)

Species-specific activity of antibacterial drug combinations

Por Brochado, Ana Rita, Telzerow, Anja, Bobonis, Jacob, Banzhaf, Manuel, Mateus, André, Selkrig, Joel, Huth, Emily, Bassler, Stefan, Zamarreño Beas, Jordi, Zietek, Matylda, Ng, Natalie, Foerster, Sunniva, Ezraty, Benjamin, Py, Béatrice, Barras, Frédéric, Savitski, Mikhail M., Bork, Peer, Göttig, Stephan, Typas, Athanasios
Publicado no Nature (2018)

Outer membrane lipoprotein NlpI scaffolds peptidoglycan hydrolases within multi‐enzyme complexes in Escherichia coli

Por Banzhaf, Manuel, Yau, Hamish CL, Verheul, Jolanda, Lodge, Adam, Kritikos, George, Mateus, André, Cordier, Baptiste, Hov, Ann Kristin, Stein, Frank, Wartel, Morgane, Pazos, Manuel, Solovyova, Alexandra S, Breukink, Eefjan, van Teeffelen, Sven, Savitski, Mikhail M, den Blaauwen, Tanneke, Typas, Athanasios, Vollmer, Waldemar
Publicado no EMBO J (2020)

The functional landscape of the human phosphoproteome

Por Ochoa, David, Jarnuczak, Andrew F., Viéitez, Cristina, Gehre, Maja, Soucheray, Margaret, Mateus, André, Kleefeldt, Askar A., Hill, Anthony, Garcia-Alonso, Luz, Stein, Frank, Krogan, Nevan J., Savitski, Mikhail M., Swaney, Danielle L., Vizcaíno, Juan A., Noh, Kyung-Min, Beltrao, Pedro
Publicado no Nat Biotechnol (2019)

A new antibiotic selectively kills Gram-negative pathogens

Por Imai, Yu, Meyer, Kirsten J., Iinishi, Akira, Favre-Godal, Quentin, Green, Robert, Manuse, Sylvie, Caboni, Mariaelena, Mori, Miho, Niles, Samantha, Ghiglieri, Meghan, Honrao, Chandrashekhar, Ma, Xiaoyu, Guo, Jason J., Makriyannis, Alexandros, Linares-Otoya, Luis, Böhringer, Nils, Wuisan, Zerlina G., Kaur, Hundeep, Wu, Runrun, Mateus, André, Typas, Athanasios, Savitski, Mikhail M., Espinoza, Josh L., O’Rourke, Aubrie, Nelson, Karen E., Hiller, Sebastian, Noinaj, Nicholas, Schäberle, Till F., D’Onofrio, Anthony, Lewis, Kim
Publicado no Nature (2019)