Thermal proteome profiling in bacteria: probing protein state in vivo

Increasing antibiotic resistance urges for new technologies for studying microbes and antimicrobial mechanism of action. We adapted thermal proteome profiling (TPP) to probe the thermostability of Escherichia coli proteins in vivo. E. coli had a more thermostable proteome than human cells, with prot...

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Detaylı Bibliyografya
Yayımlandı:Mol Syst Biol
Asıl Yazarlar: Mateus, André, Bobonis, Jacob, Kurzawa, Nils, Stein, Frank, Helm, Dominic, Hevler, Johannes, Typas, Athanasios, Savitski, Mikhail M
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2018
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056769/
https://ncbi.nlm.nih.gov/pubmed/29980614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20188242
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