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Thermal proteome profiling for interrogating protein interactions

Thermal proteome profiling (TPP) is based on the principle that, when subjected to heat, proteins denature and become insoluble. Proteins can change their thermal stability upon interactions with small molecules (such as drugs or metabolites), nucleic acids or other proteins, or upon post‐translatio...

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Detalhes bibliográficos
Publicado no:Mol Syst Biol
Main Authors: Mateus, André, Kurzawa, Nils, Becher, Isabelle, Sridharan, Sindhuja, Helm, Dominic, Stein, Frank, Typas, Athanasios, Savitski, Mikhail M
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7057112/
https://ncbi.nlm.nih.gov/pubmed/32133759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20199232
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