A new antibiotic selectively kills Gram-negative pathogens

The current need for novel antibiotics is especially acute for drug-resistant Gram-negative pathogens(1,2). These microorganisms have a highly restrictive permeability barrier, which limits penetration of most compounds(3,4). As a result, the last class of antibiotics acting against Gram-negative ba...

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Publicado no:Nature
Main Authors: Imai, Yu, Meyer, Kirsten J., Iinishi, Akira, Favre-Godal, Quentin, Green, Robert, Manuse, Sylvie, Caboni, Mariaelena, Mori, Miho, Niles, Samantha, Ghiglieri, Meghan, Honrao, Chandrashekhar, Ma, Xiaoyu, Guo, Jason J., Makriyannis, Alexandros, Linares-Otoya, Luis, Böhringer, Nils, Wuisan, Zerlina G., Kaur, Hundeep, Wu, Runrun, Mateus, André, Typas, Athanasios, Savitski, Mikhail M., Espinoza, Josh L., O’Rourke, Aubrie, Nelson, Karen E., Hiller, Sebastian, Noinaj, Nicholas, Schäberle, Till F., D’Onofrio, Anthony, Lewis, Kim
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7188312/
https://ncbi.nlm.nih.gov/pubmed/31747680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1791-1
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