A new antibiotic selectively kills Gram-negative pathogens

The current need for novel antibiotics is especially acute for drug-resistant Gram-negative pathogens(1,2). These microorganisms have a highly restrictive permeability barrier, which limits penetration of most compounds(3,4). As a result, the last class of antibiotics acting against Gram-negative ba...

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Udgivet i:Nature
Main Authors: Imai, Yu, Meyer, Kirsten J., Iinishi, Akira, Favre-Godal, Quentin, Green, Robert, Manuse, Sylvie, Caboni, Mariaelena, Mori, Miho, Niles, Samantha, Ghiglieri, Meghan, Honrao, Chandrashekhar, Ma, Xiaoyu, Guo, Jason J., Makriyannis, Alexandros, Linares-Otoya, Luis, Böhringer, Nils, Wuisan, Zerlina G., Kaur, Hundeep, Wu, Runrun, Mateus, André, Typas, Athanasios, Savitski, Mikhail M., Espinoza, Josh L., O’Rourke, Aubrie, Nelson, Karen E., Hiller, Sebastian, Noinaj, Nicholas, Schäberle, Till F., D’Onofrio, Anthony, Lewis, Kim
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7188312/
https://ncbi.nlm.nih.gov/pubmed/31747680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1791-1
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