A Cell-Free Approach Based on Phospholipid Characterization for Determination of the Cell Specific Unbound Drug Fraction (f(u,cell))

Por Treyer, Andrea, Walday, Sandra, Boriss, Hinnerk, Matsson, Pär, Artursson, Per
Publicado no Pharm Res (2019)

Intracellular drug bioavailability: a new predictor of system dependent drug disposition

Por Mateus, André, Treyer, Andrea, Wegler, Christine, Karlgren, Maria, Matsson, Pär, Artursson, Per
Publicado no Sci Rep (2017)

Impact of Intracellular Concentrations on Metabolic Drug-Drug Interaction Studies

Por Treyer, Andrea, Ullah, Mohammed, Parrott, Neil, Molitor, Birgit, Fowler, Stephen, Artursson, Per
Publicado no AAPS J (2019)

Prediction of intracellular exposure bridges the gap between target- and cell-based drug discovery

Por Mateus, André, Gordon, Laurie J., Wayne, Gareth J., Almqvist, Helena, Axelsson, Hanna, Seashore-Ludlow, Brinton, Treyer, Andrea, Matsson, Pär, Lundbäck, Thomas, West, Andy, Hann, Michael M., Artursson, Per
Publicado no Proc Natl Acad Sci U S A (2017)