In silico Druggability Assessment of the NUDIX Hydrolase Protein Family as a Workflow for Target Prioritization

gan Michel, Maurice, Homan, Evert J., Wiita, Elisée, Pedersen, Kia, Almlöf, Ingrid, Gustavsson, Anna-Lena, Lundbäck, Thomas, Helleday, Thomas, Warpman Berglund, Ulrika
Cyhoeddwyd yn Front Chem (2020)

Ebsulfur Is a Benzisothiazolone Cytocidal Inhibitor Targeting the Trypanothione Reductase of Trypanosoma brucei

gan Lu, Jun, Vodnala, Suman K., Gustavsson, Anna-Lena, Gustafsson, Tomas N., Sjöberg, Birger, Johansson, Henrik A., Kumar, Sangit, Tjernberg, Agneta, Engman, Lars, Rottenberg, Martin E., Holmgren, Arne
Cyhoeddwyd 2013

Exploiting loss of heterozygosity for allele-selective colorectal cancer chemotherapy

gan Rendo, Veronica, Stoimenov, Ivaylo, Mateus, André, Sjöberg, Elin, Svensson, Richard, Gustavsson, Anna-Lena, Johansson, Lars, Ng, Adrian, OʼBrien, Casey, Giannakis, Marios, Artursson, Per, Nygren, Peter, Cheong, Ian, Sjöblom, Tobias
Cyhoeddwyd yn Nat Commun (2020)

dUTPase inhibition augments replication defects of 5-Fluorouracil

gan Hagenkort, Anna, Paulin, Cynthia B.J., Desroses, Matthieu, Sarno, Antonio, Wiita, Elisée, Mortusewicz, Oliver, Koolmeister, Tobias, Loseva, Olga, Jemth, Ann-Sofie, Almlöf, Ingrid, Homan, Evert, Lundbäck, Thomas, Gustavsson, Anna-Lena, Scobie, Martin, Helleday, Thomas
Cyhoeddwyd yn Oncotarget (2017)

A Drosophila female pheromone elicits species-specific long-range attraction via an olfactory channel with dual specificity for sex and food

gan Lebreton, Sebastien, Borrero-Echeverry, Felipe, Gonzalez, Francisco, Solum, Marit, Wallin, Erika A., Hedenström, Erik, Hansson, Bill S., Gustavsson, Anna-Lena, Bengtsson, Marie, Birgersson, Göran, Walker, William B., Dweck, Hany K. M., Becher, Paul G., Witzgall, Peter
Cyhoeddwyd yn BMC Biol (2017)

Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells

gan Page, Brent D. G., Valerie, Nicholas C. K., Wright, Roni H. G., Wallner, Olov, Isaksson, Rebecka, Carter, Megan, Rudd, Sean G., Loseva, Olga, Jemth, Ann-Sofie, Almlöf, Ingrid, Font-Mateu, Jofre, Llona-Minguez, Sabin, Baranczewski, Pawel, Jeppsson, Fredrik, Homan, Evert, Almqvist, Helena, Axelsson, Hanna, Regmi, Shruti, Gustavsson, Anna-Lena, Lundbäck, Thomas, Scobie, Martin, Strömberg, Kia, Stenmark, Pål, Beato, Miguel, Helleday, Thomas
Cyhoeddwyd yn Nat Commun (2018)

Drug Target Commons: A Community Effort to Build a Consensus Knowledge Base for Drug-Target Interactions

gan Tang, Jing, Tanoli, Zia-ur-Rehman, Ravikumar, Balaguru, Alam, Zaid, Rebane, Anni, Vähä-Koskela, Markus, Peddinti, Gopal, van Adrichem, Arjan J., Wakkinen, Janica, Jaiswal, Alok, Karjalainen, Ella, Gautam, Prson, He, Liye, Parri, Elina, Khan, Suleiman, Gupta, Abhishekh, Ali, Mehreen, Yetukuri, Laxman, Gustavsson, Anna-Lena, Seashore-Ludlow, Brinton, Hersey, Anne, Leach, Andrew R., Overington, John P., Repasky, Gretchen, Wennerberg, Krister, Aittokallio, Tero
Cyhoeddwyd yn Cell Chem Biol (2018)

Author Correction: Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells

gan Page, Brent D. G., Valerie, Nicholas C. K., Wright, Roni H. G., Wallner, Olov, Isaksson, Rebecka, Carter, Megan, Rudd, Sean G., Loseva, Olga, Jemth, Ann-Sofie, Almlöf, Ingrid, Font-Mateu, Jofre, Llona-Minguez, Sabin, Baranczewski, Pawel, Jeppsson, Fredrik, Homan, Evert, Almqvist, Helena, Axelsson, Hanna, Regmi, Shruti, Gustavsson, Anna-Lena, Lundbäck, Thomas, Scobie, Martin, Strömberg, Kia, Stenmark, Pål, Beato, Miguel, Helleday, Thomas
Cyhoeddwyd yn Nat Commun (2019)

A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage

gan Ladds, Marcus J. G. W., van Leeuwen, Ingeborg M. M., Drummond, Catherine J., Chu, Su, Healy, Alan R., Popova, Gergana, Pastor Fernández, Andrés, Mollick, Tanzina, Darekar, Suhas, Sedimbi, Saikiran K., Nekulova, Marta, Sachweh, Marijke C. C., Campbell, Johanna, Higgins, Maureen, Tuck, Chloe, Popa, Mihaela, Safont, Mireia Mayoral, Gelebart, Pascal, Fandalyuk, Zinayida, Thompson, Alastair M., Svensson, Richard, Gustavsson, Anna-Lena, Johansson, Lars, Färnegårdh, Katarina, Yngve, Ulrika, Saleh, Aljona, Haraldsson, Martin, D’Hollander, Agathe C. A., Franco, Marcela, Zhao, Yan, Håkansson, Maria, Walse, Björn, Larsson, Karin, Peat, Emma M., Pelechano, Vicent, Lunec, John, Vojtesek, Borivoj, Carmena, Mar, Earnshaw, William C., McCarthy, Anna R., Westwood, Nicholas J., Arsenian-Henriksson, Marie, Lane, David P., Bhatia, Ravi, McCormack, Emmet, Laín, Sonia
Cyhoeddwyd yn Nat Commun (2018)

Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage

gan Ladds, Marcus J. G. W., van Leeuwen, Ingeborg M. M., Drummond, Catherine J., Chu, Su, Healy, Alan R., Popova, Gergana, Pastor Fernández, Andrés, Mollick, Tanzina, Darekar, Suhas, Sedimbi, Saikiran K., Nekulova, Marta, Sachweh, Marijke C. C., Campbell, Johanna, Higgins, Maureen, Tuck, Chloe, Popa, Mihaela, Safont, Mireia Mayoral, Gelebart, Pascal, Fandalyuk, Zinayida, Thompson, Alastair M., Svensson, Richard, Gustavsson, Anna-Lena, Johansson, Lars, Färnegårdh, Katarina, Yngve, Ulrika, Saleh, Aljona, Haraldsson, Martin, D’Hollander, Agathe C. A., Franco, Marcela, Zhao, Yan, Håkansson, Maria, Walse, Björn, Larsson, Karin, Peat, Emma M., Pelechano, Vicent, Lunec, John, Vojtesek, Borivoj, Carmena, Mar, Earnshaw, William C., McCarthy, Anna R., Westwood, Nicholas J., Arsenian-Henriksson, Marie, Lane, David P., Bhatia, Ravi, McCormack, Emmet, Laín, Sonia
Cyhoeddwyd yn Nat Commun (2018)