From whole-mount to single-cell spatial assessment of gene expression in 3D

door Waylen, Lisa N., Nim, Hieu T., Martelotto, Luciano G., Ramialison, Mirana
Gepubliceerd in Commun Biol (2020)

Single-Cell Applications of Next-Generation Sequencing

door Anaparthy, Naishitha, Ho, Yu-Jui, Martelotto, Luciano, Hammell, Molly, Hicks, James
Gepubliceerd in Cold Spring Harb Perspect Med (2019)

Breast cancer intra-tumor heterogeneity

door Martelotto, Luciano G, Ng, Charlotte KY, Piscuoglio, Salvatore, Weigelt, Britta, Reis-Filho, Jorge S
Gepubliceerd in 2014

Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations

door Martelotto, Luciano G, Ng, Charlotte KY, De Filippo, Maria R, Zhang, Yan, Piscuoglio, Salvatore, Lim, Raymond S, Shen, Ronglai, Norton, Larry, Reis-Filho, Jorge S, Weigelt, Britta
Gepubliceerd in Genome Biol (2014)

Generation of conditional oncogenic chromosomal translocations using CRISPR-Cas9 genomic editing and homology-directed repair

door Spraggon, Lee, Martelotto, Luciano G, Hmeljak, Julija, Hitchman, Tyler D, Wang, Jiang, Wang, Lu, Slotkin, Emily K, Fan, Pang-Dian, Reis-Filho, Jorge S, Ladanyi, Marc
Gepubliceerd in J Pathol (2017)

MED12 somatic mutations in fibroadenomas and phyllodes tumors of the breast

door Piscuoglio, Salvatore, Murray, Melissa, Fusco, Nicola, Marchiò, Caterina, Loo, Florence L, Martelotto, Luciano G, Schultheis, Anne M, Akram, Muzaffar, Weigelt, Britta, Brogi, Edi, Reis-Filho, Jorge S
Gepubliceerd in Histopathology (2015)

TP53 Mutational Spectrum in Endometrioid and Serous Endometrial Cancers

door Schultheis, Anne M, Martelotto, Luciano G, De Filippo, Maria R, Piscuoglio, Salvatore, Ng, Charlotte K Y, Hussein, Yaser R, Reis-Filho, Jorge S, Soslow, Robert A, Weigelt, Britta
Gepubliceerd in Int J Gynecol Pathol (2016)

Lack of PRKD2 and PRKD3 kinase domain somatic mutations in PRKD1 wild-type classic polymorphous low-grade adenocarcinomas of the salivary gland

door Piscuoglio, Salvatore, Fusco, Nicola, Ng, Charlotte KY, Martelotto, Luciano G, da Cruz Paula, Arnaud, Katabi, Nora, Rubin, Brian P, Skálová, Alena, Weinreb, Ilan, Weigelt, Britta, Reis-Filho, Jorge S
Gepubliceerd in Histopathology (2016)

Renal epithelial cells retain primary cilia during human acute renal allograft rejection injury

door Verghese, Elizabeth, Martelotto, Luciano G., Cain, Jason E., Williams, Timothy M., Wise, Andrea F., Hill, Prudence A., Langham, Robyn G., Watkins, D. Neil, Ricardo, Sharon D., Deane, James A.
Gepubliceerd in BMC Res Notes (2019)

Resolving quandaries: basaloid adenoid cystic carcinoma or breast cylindroma? The role of massively parallel sequencing

door Fusco, Nicola, Colombo, Pierre-Emmanuel, Martelotto, Luciano G., De Filippo, Maria R., Piscuoglio, Salvatore, Ng, Charlotte K.Y., Lim, Raymond S., Jacot, William, Vincent-Salomon, Anne, Reis-Filho, Jorge S., Weigelt, Britta
Gepubliceerd in Histopathology (2015)

Next-Generation Sequence Analysis of Cancer Xenograft Models

door Rossello, Fernando J., Tothill, Richard W., Britt, Kara, Marini, Kieren D., Falzon, Jeanette, Thomas, David M., Peacock, Craig D., Marchionni, Luigi, Li, Jason, Bennett, Samara, Tantoso, Erwin, Brown, Tracey, Chan, Philip, Martelotto, Luciano G., Watkins, D. Neil
Gepubliceerd in 2013

Integrative genomic and transcriptomic characterization of papillary carcinomas of the breast

door Piscuoglio, Salvatore, Ng, Charlotte K.Y., Martelotto, Luciano G., Eberle, Carey A., Cowell, Catherine F., Natrajan, Rachael, Bidard, François-Clement, De Mattos-Arruda, Leticia, Wilkerson, Paul M., Mariani, Odette, Vincent-Salomon, Anne, Weigelt, Britta, Reis-Filho, Jorge S.
Gepubliceerd in Mol Oncol (2014)

Genetic instability and recurrent MYC amplification in ALK‐translocated NSCLC: a central role of TP53 mutations

door Alidousty, Christina, Baar, Till, Martelotto, Luciano G, Heydt, Carina, Wagener, Svenja, Fassunke, Jana, Duerbaum, Nicolai, Scheel, Andreas H, Frank, Sandra, Holz, Barbara, Binot, Elke, Kron, Anna, Merkelbach‐Bruse, Sabine, Ihle, Michaela A, Wolf, Jürgen, Buettner, Reinhard, Schultheis, Anne Maria
Gepubliceerd in J Pathol (2018)

SUGAR-seq enables simultaneous detection of glycans, epitopes, and the transcriptome in single cells

door Kearney, Conor J., Vervoort, Stephin J., Ramsbottom, Kelly M., Todorovski, Izabela, Lelliott, Emily J., Zethoven, Magnus, Pijpers, Lizzy, Martin, Ben P., Semple, Timothy, Martelotto, Luciano, Trapani, Joseph A., Parish, Ian A., Scott, Nichollas E., Oliaro, Jane, Johnstone, Ricky W.
Gepubliceerd in Sci Adv (2021)

A P53-Independent DNA Damage Response Suppresses Oncogenic Proliferation and Genome Instability

door Fagan-Solis, Katerina D., Simpson, Dennis A., Kumar, Rashmi J., Martelotto, Luciano G., Mose, Lisle E., Rashid, Naim U., Ho, Alice Y., Powell, Simon N., Wen, Y. Hannah, Parker, Joel S., Reis-Filho, Jorge S., Petrini, John H.J., Gupta, Gaorav P.
Gepubliceerd in Cell Rep (2020)

Genomic and transcriptomic heterogeneity in metaplastic carcinomas of the breast

door Piscuoglio, Salvatore, Ng, Charlotte K. Y., Geyer, Felipe C., Burke, Kathleen A., Cowell, Catherine F., Martelotto, Luciano G., Natrajan, Rachael, Popova, Tatiana, Maher, Christopher A., Lim, Raymond S., Bruijn, Ino de, Mariani, Odette, Norton, Larry, Vincent-Salomon, Anne, Weigelt, Britta, Reis-Filho, Jorge S.
Gepubliceerd in NPJ Breast Cancer (2017)

Widespread GLI expression but limited canonical hedgehog signaling restricted to the ductular reaction in human chronic liver disease

door Grzelak, Candice Alexandra, Sigglekow, Nicholas David, Tirnitz-Parker, Janina Elke Eleonore, Hamson, Elizabeth Jane, Warren, Alessandra, Maneck, Bharvi, Chen, Jinbiao, Patkunanathan, Bramilla, Boland, Jade, Cheng, Robert, Shackel, Nicholas Adam, Seth, Devanshi, Bowen, David Geoffrey, Martelotto, Luciano Gastón, Watkins, D. Neil, McCaughan, Geoffrey William
Gepubliceerd in PLoS One (2017)

Uterine adenosarcomas are mesenchymal neoplasms

door Piscuoglio, Salvatore, Burke, Kathleen A, Ng, Charlotte KY, Papanastasiou, Anastasios D, Geyer, Felipe C, Macedo, Gabriel S, Martelotto, Luciano G, de Bruijn, Ino, De Filippo, Maria R, Schultheis, Anne M, Ioris, Rafael A, Levine, Douglas A, Soslow, Robert A, Rubin, Brian P, Reis-Filho, Jorge S, Weigelt, Britta
Gepubliceerd in J Pathol (2015)

MYBL1 rearrangements and MYB amplification in breast adenoid cystic carcinomas lacking the MYB-NFIB fusion gene

door Kim, Jisun, Geyer, Felipe C., Martelotto, Luciano G, Ng, Charlotte K Y, Lim, Raymond S, Selenica, Pier, Li, Anqi, Pareja, Fresia, Fusco, Nicola, Edelweiss, Marcia, Kumar, Rahul, Gularte-Merida, Rodrigo, Forbes, Andre N, Khurana, Ekta, Mariani, Odette, Badve, Sunil, Vincent-Salomon, Anne, Norton, Larry, Reis-Filho, Jorge S, Weigelt, Britta
Gepubliceerd in J Pathol (2017)

The repertoire of somatic genetic alterations of acinic cell carcinomas of the breast: an exploratory, hypothesis-generating study

door Guerini-Rocco, Elena, Hodi, Zsolt, Piscuoglio, Salvatore, Ng, Charlotte KY, Rakha, Emad A, Schultheis, Anne M, Marchiò, Caterina, Paula, Arnaud da Cruz, De Filippo, Maria R, Martelotto, Luciano G, De Mattos-Arruda, Leticia, Edelweiss, Marcia, Jungbluth, Achim A, Fusco, Nicola, Norton, Larry, Weigelt, Britta, Ellis, Ian O, Reis-Filho, Jorge S
Gepubliceerd in J Pathol (2015)