SUGAR-seq enables simultaneous detection of glycans, epitopes, and the transcriptome in single cells

Multimodal single-cell RNA sequencing enables the precise mapping of transcriptional and phenotypic features of cellular differentiation states but does not allow for simultaneous integration of critical posttranslational modification data. Here, we describe SUrface-protein Glycan And RNA-seq (SUGAR...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Adv
Prif Awduron: Kearney, Conor J., Vervoort, Stephin J., Ramsbottom, Kelly M., Todorovski, Izabela, Lelliott, Emily J., Zethoven, Magnus, Pijpers, Lizzy, Martin, Ben P., Semple, Timothy, Martelotto, Luciano, Trapani, Joseph A., Parish, Ian A., Scott, Nichollas E., Oliaro, Jane, Johnstone, Ricky W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Association for the Advancement of Science 2021
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7895430/
https://ncbi.nlm.nih.gov/pubmed/33608275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abe3610
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