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DOCK8 regulates signal transduction events to control immunity

Genetic mutations in the gene encoding DOCK8 cause an autosomal recessive form of hyper immunoglobulin E syndrome (AR-HIES), referred to as DOCK8 deficiency. DOCK8 deficiency in humans results in the onset of combined immunodeficiency disease (CID), clinically associated with chronic infections with...

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Detalhes bibliográficos
Publicado no:Cell Mol Immunol
Main Authors: Kearney, Conor J, Randall, Katrina L, Oliaro, Jane
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423093/
https://ncbi.nlm.nih.gov/pubmed/28366940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2017.9
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