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Netrin signal transduction and the guanine nucleotide exchange factor DOCK180 in attractive signaling
Netrins are prototypical axon guidance cues whose attractive signaling requires the small GTPase Rac1. It remains unclear how Rac1 is regulated in the netrin pathway. DOCK180 is a member of a new family of guanine nucleotide exchange factors for Rho GTPases. Here we provide evidence implicating DOCK...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2262939/ https://ncbi.nlm.nih.gov/pubmed/18066058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn2022 |
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