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A Minimal Rac Activation Domain in the Unconventional Guanine Nucleotide Exchange Factor Dock180
Guanine nucleotide exchange factors (GEFs) activate Rho GTPases by catalyzing the exchange of bound GDP for GTP, thereby resulting in downstream effector recognition. Two metazoan families of GEFs have been described: Dbl-GEF family members that share conserved Dbl homology (DH) and Pleckstrin homol...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3048587/ https://ncbi.nlm.nih.gov/pubmed/21033699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100971y |
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