Guanine nucleotide exchange factor Dock7 mediates HGF-induced glioblastoma cell invasion via Rac activation

BACKGROUND: Glioblastoma multiforme (GBM), a highly invasive primary brain tumour, remains an incurable disease. Rho GTPases and their activators, guanine nucleotide exchange factors (GEFs), have central roles in GBM invasion. Anti-angiogenic therapies may stimulate GBM invasion via HGF/c-Met signal...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Murray, D W, Didier, S, Chan, A, Paulino, V, Van Aelst, L, Ruggieri, R, Tran, N L, Byrne, A T, Symons, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3950876/
https://ncbi.nlm.nih.gov/pubmed/24518591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.39
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados